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Urine Creatinine Clearance Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products from your blood by analyzing your urine and blood creatinine levels over a 24-hour period.

Quick summary

["Assesses kidney function by estimating how efficiently your kidneys clear waste."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13872-7
Short code
11DC 24h Ur-mRate
Synonyms
11DC 24h Ur-mRate
Category
hormone
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Urine creatinine clearance evaluates the rate at which creatinine—a waste product from muscle metabolism—is removed from your blood through your kidneys. It combines measurements of creatinine concentration in your urine and blood over a full day to calculate how effectively your kidneys are functioning.

Why Might You Need This Test?

Doctors may order urine creatinine clearance to diagnose or monitor kidney disease, track kidney function before or after treatments, or evaluate kidney health in people with conditions like diabetes or high blood pressure.

How Is This Test Performed?

You’ll collect all urine for a full 24-hour period in a special container. Blood is drawn once at the start or end of the collection period to measure creatinine levels. The test compares urine and blood samples to estimate your kidney function.

What Are Common Results?

Results are typically reported as a clearance rate (e.g., in milliliters per minute or liters per day). Lower than expected values may indicate kidney problems, while higher values could suggest overhydration or other conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Kidney Function Assessment

Short name

Urine Creatinine Clearance

Frequently asked questions

How often should I expect this test?
This test is usually performed only when needed for diagnosis, monitoring, or specific medical reasons. Your doctor will determine if repeat testing is required based on your health status and treatment plan.
What does a low clearance rate mean?
A low clearance rate often suggests impaired kidney function, which could indicate early kidney disease or other conditions affecting kidney health. It’s important to discuss results with your healthcare provider to understand potential causes and next steps.
Can I eat or drink normally before this test?
Yes, you can eat and drink as usual during the 24-hour urine collection period, unless your doctor specifies otherwise. Avoiding certain medications or foods may be advised, so follow your healthcare provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy