Serum or plasma mass concentration of a specific protein (e.g., albumin, globulin, or other protein marker)

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like swelling, unexplained weight changes, fatigue, or if they suspect conditions such as protein-losing disorders, kidney disease, or liver problems. It may also be used to monitor chronic conditions like heart failure or certain cancers.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours if the test involves a specific protein related to digestion or metabolism. Avoid smoking or caffeine for 30 minutes before the draw if instructed. Bring any medications you’re taking to your appointment.

During the Test Process

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick. The blood sample will be sent to a lab for analysis. If this is a 24-hour urine test (if applicable), you’ll need to collect urine in a container over the specified period.

What the Results Mean

Results will show the mass concentration of the protein in your blood or urine. While reference ranges vary by protein and lab, lower or higher-than-expected levels may signal underlying health issues. Your provider will interpret results in the context of your medical history and symptoms.