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Serum or plasma mass concentration of aldosterone

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of aldosterone, a hormone produced by your adrenal glands that helps regulate blood pressure and fluid balance.

Quick summary

["Aldosterone helps control how much sodium and potassium your body retains, which affects blood pressure and fluid levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16295-8
Short code
11DC p chal SerPl-mCnc
Synonyms
11DC p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to help your healthcare provider check how well your body is working, look for signs of illness, confirm or rule out a suspected condition, or monitor a health problem you already have. It may also be part of a routine checkup or used to see how well a current treatment is working for you.

Your doctor may order this test to diagnose or monitor conditions like primary aldosteroneism (hyperaldosteronism), adrenal insufficiency, or to check for hormonal imbalances affecting blood pressure or kidney function. It can also help evaluate symptoms such as high blood pressure, low potassium levels, or unexplained fluid retention.

Your result shows whether the measured value falls within the typical range for healthy adults. A value outside that range does not automatically mean you are sick, because many factors can affect it. Your healthcare provider will interpret the result together with your symptoms, medical history, and other test findings before deciding what it means for you.

Higher-than-normal levels may suggest conditions like aldosterone excess, which can lead to high blood pressure or low potassium. Lower-than-normal levels might indicate adrenal gland problems or other hormonal disorders. Your doctor will interpret results in the context of your overall health and symptoms.

The test is usually a simple procedure performed in a clinic, hospital, or laboratory. A trained member of the care team collects a small sample, such as blood or urine, using clean, sterile equipment. The sample is then sent to a laboratory where specialists analyze it, and the collection step itself usually takes only a few minutes.

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is processed to separate serum or plasma, then analyzed to measure aldosterone concentration using mass spectrometry.

Before the test, follow any specific instructions from your healthcare provider. You may be asked to avoid eating or drinking for a period of time, temporarily stop certain medicines or supplements, or drink extra water. Tell the care team about all medications you take, and let them know if you are pregnant or have any allergies.

Avoid taking certain medications (like some blood pressure drugs) that may affect aldosterone levels for a few days before testing. Also, inform your doctor about any supplements or over-the-counter medications you’re taking. You may need to fast for a set period, but your doctor will let you know.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

How does this test relate to health?

Short name

Aldosterone level

Frequently asked questions

Abnormal aldosterone levels can cause serious health issues, such as high blood pressure, kidney problems, or irregular heart rhythms. Regular monitoring can help manage conditions like hypertension or adrenal disorders, preventing complications like heart disease or stroke.
Common causes of abnormal results include infections, inflammation, dehydration, physical stress, recent exercise, and side effects of prescription or over-the-counter medicines and supplements. Long-term conditions such as diabetes, thyroid disease, or kidney and liver problems can also change results. Sometimes an abnormal value is simply a normal lab variation, so your provider may order a repeat test to confirm.
High aldosterone levels can result from conditions like primary aldosteronism, kidney disease, or certain medications. Low levels may be linked to adrenal gland disorders, such as Addison’s disease, or conditions affecting hormone production.
How often this test should be repeated depends on why it was ordered and on your overall health. Some people need it only once for screening, while others who are being treated or monitored for a condition may need it every few weeks or months. Your healthcare provider will set the schedule that is right for you and adjust it if your condition changes over time.
Your doctor will determine how often to repeat this test based on your diagnosis, symptoms, and treatment plan. Some patients need monitoring every few months or annually, while others may need it more frequently.
The most common risk is a slight bruise or discomfort at the injection site. Rarely, there may be a reaction to the needle or blood draw, but serious complications are uncommon.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy