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Serum or plasma concentration of metyrapone (a drug metabolite or related substance)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a substance derived from the medication metyrapone in your blood, often used to monitor drug metabolism or assess kidney function.

Quick summary

["Helps track how your body processes metyrapone or evaluates kidney function in certain tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41289-0
Short code
11DC p metyraPONE SerPl-mCnc
Synonyms
11DC p metyraPONE SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may request this test if you’re taking metyrapone (a medication used to treat conditions like congenital adrenal hyperplasia) or if they suspect issues with how your kidneys filter substances from your blood.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast or avoid certain medications for a short time before the blood draw. Bring your medication list to confirm.

How the Test Works

A small sample of your blood (serum or plasma) is collected and analyzed to measure the concentration of metyrapone metabolites. The test may use methods like immunoassay or chromatography to detect the substance.

What the Results Mean

Results help determine if your kidneys are functioning properly or if metyrapone is being processed as expected. Abnormal levels may indicate kidney problems or drug interactions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated levels of metyrapone metabolites may suggest impaired kidney function or excessive drug exposure, while lower levels could indicate faster metabolism. This test is often part of a broader evaluation for conditions like adrenal disorders or renal impairment.

Short name

Metyrapone metabolite concentration

Frequently asked questions

What does a normal result mean?
A normal result typically means your kidneys are filtering the substance appropriately, or your body is processing metyrapone as expected. However, reference ranges can vary by lab, so discuss results with your provider.
How often should I get this test?
The frequency depends on your treatment plan. Your healthcare provider will schedule follow-up tests based on your medical needs, such as monitoring kidney function or drug levels.
Can I eat or drink before this test?
Check with your provider about fasting requirements, as some tests may require avoiding food or fluids for a short period before drawing blood.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy