11-Dehydrocorticosterone+tetrahydrocorticosterone+Allo-tetrahydrocorticosterone/Tetrahydro
Measures six cortisol and corticosterone pathway metabolites in urine to help evaluate adrenal steroid production and metabolism.
This urine panel helps clinicians identify changes in cortisol and corticosterone metabolism that may indicate an adrenal or steroid-processing disorder.
Key facts at a glance
- LOINC
- 82848-3
- Short code
- 11-DHC+THB+5a-THB/THE+THF+5a-THF Ur-sRto
- Synonyms
- 11-DHC+THB+5a-THB/THE+THF+5a-THF Ur-sRto
- Category
- liver
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 36
- Ref high
- 50
- Critical range
- 18 N/A – 60 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85014
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures metabolites formed as the body processes cortisol and corticosterone. It includes 11-dehydrocorticosterone, tetrahydrocorticosterone, 5α-tetrahydrocorticosterone, tetrahydrocortisone, tetrahydrocortisol, and 5α-tetrahydrocortisol.
Why might I need this test?
This panel may be ordered when symptoms suggest an adrenal steroid disorder or when there is concern about an inherited problem in cortisol metabolism. It can help evaluate possible 11β-hydroxysteroid dehydrogenase or related enzyme abnormalities.
How is the test performed?
A urine specimen is collected and the steroid metabolites are measured in a laboratory. Your clinician will tell you whether a single sample or a timed collection, such as a 24-hour collection, is required.
How do I prepare for the test?
Follow the collection instructions provided by your clinician and use the specified urine container. For a timed collection, record the start and finish times and collect all urine during that period; do not stop prescribed medicines unless instructed.
Reference range
Adult males: 38-50%; Females: 36-44%N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal metabolite levels or ratios may indicate altered cortisol and corticosterone metabolism, including an adrenal steroid-production disorder or an inherited enzyme deficiency. Results should be interpreted with symptoms, medication use, and other adrenal hormone tests because collection timing and medications can affect the results.
Short name
Urinary corticosteroid metabolite panel
Frequently asked questions
What does this urine panel measure?
Why are the results examined together?
Does an abnormal result confirm a specific diagnosis?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy