14dioxaneairmcnc

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures 1,4-dioxane levels in your body to assess exposure to this chemical compound.

Quick summary

{"Measures 1,4-dioxane, a chemical used in industrial solvents","Helps determine if you have been exposed to 1,4-dioxane through work or environment","Results help your doctor monitor your exposure and recommend protective measures","This test is often used for occupational health monitoring","No special preparation is typically needed for this blood test"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC: 38593-0
Short code: 1,4-DIOX
Synonyms: 1,4Dioxane Air-mCnc
Category: chemistry
Sample: serum
Container: Serum separator tube (SST) or plain red top tube; specific air sampling media (activated charcoal tubes or passive dosimeters) if air testing
Units: N/A
Fasting: false
Population: adult
Sex: all
Age range: 18–65 years
Method: Gas chromatography-mass spectrometry (GC-MS) or Solid-phase microextraction (SPME) with GC-MS analysis
CPT: 84600 (Volatile organic compound(s) analysis, not elsewhere specified) or 83018 (unspecified toxicology screen)
SNOMED: 372729009 (1,4-Dioxane measurement) or 268651007 (Occupational exposure assessment)
Specimen volume: 5-10 mL venous blood for serum; air volume depends on method (typically 1-10 liters for occupational sampling)
Stability: Serum: refrigerate at 2-8°C for up to 7 days; freeze at -20°C or below for longer storage; protect from light as 1,4-Dioxane may be volatile
Hemolysis max: 500
Lipemia max: 1000
Icterus max: 500
TAT: 72–168 hours
Order: routine

What is this test?

The 1,4-Dioxane test measures the amount of 1,4-dioxane in your blood serum. 1,4-Dioxane is a colorless liquid chemical compound primarily used as a solvent in industrial processes, including the production of chemicals, plastics, and some consumer products. This test helps determine if you have been exposed to 1,4-dioxane and at what level. It is commonly performed for occupational health monitoring, especially in workers who handle or are exposed to this chemical in manufacturing or industrial settings.

Reference range

No established reference range for serum; occupational exposure limit (OEL) for air: 1,4-Dioxane ≤ 1 ppm (3.6 mg/m³) as 8-hour TWA; biological exposure index (BEI) not establishedN/A

Specimen: serum

No specific preparation required; avoid exposure to 1,4-Dioxane-containing products (certain cosmetics, detergents, adhesives) for 24 hours prior to collection if possible; inform laboratory of occupational exposure history

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The 1,4-Dioxane test is primarily used for occupational health surveillance to monitor exposure levels in workers handling this chemical. Elevated levels may indicate excessive exposure, which could pose health risks including potential effects on the liver and kidneys. Regular monitoring helps ensure workplace safety and compliance with occupational exposure limits. This test may also be used in environmental health assessments when community exposure to 1,4-dioxane is suspected.

Frequently asked questions

Why would I need this test?

You may need this test if you work in an industry where 1,4-dioxane is used or produced, such as chemical manufacturing, plastics production, or certain laboratory settings. It is often part of routine occupational health monitoring to ensure your exposure levels remain within safe limits.

Is the test safe?

Yes, this is a standard blood test with minimal risks. You may experience slight bruising or tenderness at the needle site. The amount of blood drawn is small and well within safe limits.

How should I prepare for this test?

No special preparation is typically required. You should follow your doctor's instructions regarding any medications you are taking. Inform your healthcare provider about any chemicals you may have been exposed to recently.

What do the results mean?

Your test results will show the concentration of 1,4-dioxane in your blood. Your doctor will interpret these results based on occupational exposure guidelines and your specific work environment. Elevated levels may require protective measures or changes in workplace procedures.

Sources

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy