17ohp24hurmrate
A 24-hour urine test measuring 17-hydroxyprogesterone levels to help diagnose and monitor congenital adrenal hyperplasia (CAH) and certain adrenal disorders.
{"This test measures 17-hydroxyprogesterone hormone in a 24-hour urine collection","It primarily helps diagnose and monitor congenital adrenal hyperplasia (CAH)","Proper urine collection over 24 hours is critical for accurate results","Results are compared to age and gender-specific reference ranges","Abnormal results may require additional testing for confirmation"}
Key facts at a glance
- LOINC
- 9616-4
- Short code
- 17-OHP 24h U
- Synonyms
- 17OHP 24h Ur-mRate
- Category
- chemistry
- Sample
- urine
- Container
- 24-hour urine collection container (plastic, sterile, graduated)
- Units
- N/A
- Ref low
- 0.5
- Ref high
- 5
- Critical range
- — – 15 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
- CPT
- 83498
- SNOMED
- 313295004
- Specimen volume
- Complete 24-hour collection, minimum 10 mL aliquot for analysis
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days. Protect from light.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 72–168 hours
- Order
- routine
What is this test?
The 17-Hydroxyprogesterone (17-OHP) urine test measures the amount of 17-hydroxyprogesterone, a steroid hormone produced by the adrenal glands, in your urine collected over a 24-hour period. This hormone is an intermediate in the production of cortisol, a vital stress hormone. The test helps healthcare providers evaluate how well your adrenal glands are functioning and screen for certain hormonal disorders.
During the 24-hour collection period, you will be given a special container to collect all urine produced. It is important to collect every urine sample during this time period, including the first morning urine on day 2, as the test measures the total hormone output over a full day. The container should be kept refrigerated or in a cool place during collection.
Reference range
0.5-5.0 µg/24h (adults); Reference ranges vary by age, sex, and clinical context. Consult laboratory for age-specific reference intervals.N/A
No special preparation required. Maintain normal hydration. Avoid vitamin C supplements 24 hours prior to collection as ascorbic acid may interfere with some assay methodologies. Collect urine in preservative-free container for LC-MS/MS methodology.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings3
Frequently asked questions
Why is a 24-hour urine collection needed instead of a single sample?
Do I need to fast before this test?
What happens if my results are abnormal?
Can this test be done in children?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy