Complete Blood Count (CBC): A Blood Test That Checks Your Red Blood Cells, White Blood Cells, and Platelets
This blood test measures 17-hydroxyprogesterone levels in your blood after receiving a hormone injection to help diagnose adrenal gland disorders.
{"Measures hormone levels to check adrenal gland function","Involves multiple blood draws after a hormone injection (GnRH)","Mainly used to diagnose congenital adrenal hyperplasia (CAH)","Helps doctors understand hormone problems affecting growth and development","A simple blood test with minimal risks"}
Key facts at a glance
- LOINC
- 57543-1
- Short code
- 17-OHP
- Synonyms
- 17OHP sp6 p GnRH SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST, gold top) or plain red top tube
- Units
- N/A
- Ref low
- 0.5
- Ref high
- 10
- Critical range
- — – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Immunoassay (Chemiluminescent or Electrochemiluminescent)
- CPT
- 83498
- SNOMED
- 31331008
- Specimen volume
- 1.0-2.0 mL serum minimum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 20
- TAT
- 24–72 hours
- Order
- routine
This test is a complete blood count, commonly called a CBC. It measures the main types of cells in your blood, including red blood cells, white blood cells, and platelets, and it helps your healthcare provider evaluate your overall health and detect many different conditions.
The 17-Hydroxyprogesterone (17-OHP) test measures the amount of a specific hormone in your blood. This test is done after you receive an injection of Gonadotropin Releasing Hormone (GnRH), which stimulates your body to produce certain hormones. Multiple blood samples are collected (this is the 6th specimen) to see how your adrenal glands and pituitary gland respond over time.
Your provider may order this test as part of a routine checkup, or to help find the cause of symptoms such as fatigue, weakness, fever, easy bruising, or unusual bleeding. It can also be used to monitor an existing condition, such as anemia, or to see how well a treatment is working.
Your doctor may order this test if you or your child has symptoms of a hormone disorder, such as early or delayed puberty, ambiguous genitalia, or unusual growth patterns. The test helps doctors determine if the adrenal glands are producing too much or too little of certain hormones, which can indicate conditions like Congenital Adrenal Hyperplasia (CAH) or other hormonal imbalances.
A healthcare professional will take a small sample of blood, usually from a vein in your arm. The site is cleaned, a needle is gently inserted, and the blood is collected into a tube and sent to a laboratory for analysis. The procedure typically takes only a few minutes and causes little discomfort.
A healthcare provider will first give you a GnRH injection, usually in the arm. Then, blood samples will be taken at specific time intervals (this is the 6th and final sample). Each blood draw involves inserting a small needle into a vein to collect a small amount of blood. The entire process may take several hours.
This test usually requires no special preparation, and you can normally eat and drink beforehand unless your provider tells you otherwise. Tell your provider about all medicines and supplements you take, since some can affect results. Wear a short sleeve or a sleeve that rolls up easily, and let the staff know if you have ever felt faint during blood draws.
Follow your doctor's instructions about eating and drinking before the test. Some medications may affect the test results, so inform your doctor about all medicines, vitamins, or supplements you are taking. Wear comfortable clothing with sleeves that can be easily rolled up for the blood draw.
Reference range
Reference range for GnRH-stimulated 17-OHP varies by protocol and laboratory. Baseline (0 min): <2.0 ng/dL; Peak (30-60 min post GnRH): <5.0 ng/dL in adults; Peak (60 min): <10.0 ng/dL in children. Specific reference ranges should be derived from the testing laboratory's validated protocol for the GnRH stimulation test.N/A
No fasting required. Patient should inform the laboratory of current medications, particularly corticosteroids, hormonal contraceptives, or medications affecting steroidogenesis. Specimen collected as part of standardized GnRH stimulation protocol with specific timing requirements.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used to diagnose and monitor Congenital Adrenal Hyperplasia (CAH), a genetic condition where the adrenal glands produce abnormal amounts of hormones. It also helps differentiate between adrenal and gonadal sources of hormone production, which is useful in evaluating disorders of sex development (DSD) and pituitary function. The GnRH stimulation test specifically helps doctors understand how the body's hormone regulation system responds to stimulation, providing more detailed information than a single hormone measurement.
Frequently asked questions
Is the GnRH injection safe?
How long does the entire test take?
Will the test be painful?
When will I get my results?
Are there any risks to this test?
Sources
- 1
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Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy