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24hpredictedproturcalcmrate

Published: August 9, 2026Updated: August 16, 2026

This test estimates the amount of protein in your urine over 24 hours using a single urine sample.

Quick summary

{"Measures protein in urine to assess kidney function","Uses a single urine sample to predict 24-hour protein excretion","Helps diagnose and monitor kidney disease","Higher than normal levels may indicate kidney damage","Results are reported as a ratio comparing protein to creatinine"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96803-2
Short code
24hUPred
Synonyms
24H predicted prot Ur Calc-mRate
Category
chemistry
Sample
serum
Container
Sterile urine collection container (random clean-catch or midstream)
Units
N/A
Ref low
0
Ref high
150
Critical range
— – 3000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–100 years
Method
calculated
CPT
82043
SNOMED
271344004
Specimen volume
10-50 mL random urine aliquot
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): 2 weeks
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The 24-hour predicted protein test estimates how much protein your kidneys are leaking into your urine over a 24-hour period. Normally, healthy kidneys filter waste from your blood while keeping important proteins in your body. When kidneys are damaged, they may allow proteins like albumin to leak into urine.

How does the test work?

Instead of collecting all urine for 24 hours, this test uses a single random urine sample. It measures both protein and creatinine (a waste product) in your urine and calculates a ratio. This protein-to-creatinine ratio (PCR) is then used to estimate your 24-hour protein excretion. Creatinine is excreted at a relatively constant rate, making it a useful reference point.

Why is this test important?

Protein in urine (proteinuria) is an important sign of kidney damage. Early detection of kidney problems allows for better management and can prevent further damage. This test is commonly used to monitor patients with diabetes, high blood pressure, or known kidney disease.

How to prepare for the test

No special preparation is usually needed for this test. You may be asked to avoid certain medications or strenuous exercise before the test, as these can affect results. Follow any specific instructions from your healthcare provider.

Reference range

Normal: <150 mg/24h or <150 mg/g creatinine; Abnormal: >150 mg/24h indicates proteinuriaN/A

Specimen: serum

No specific fasting required. Collect random urine sample preferably in morning. Avoid vigorous exercise 24 hours prior to collection as it may cause transient proteinuria. Inform clinician of any recent infections or medications that may affect kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Is this test better than a 24-hour urine collection?
This test is more convenient as it only requires one urine sample instead of collecting all urine for 24 hours. However, the 24-hour collection is still considered the gold standard for accuracy. Your doctor will determine which test is appropriate for your situation.
Does having protein in urine always mean kidney disease?
Not always. Small amounts of protein in urine can sometimes be normal, especially after exercise or during illness. However, persistent protein in urine is usually a sign of kidney damage and should be evaluated by your healthcare provider.
Will I have symptoms if I have protein in my urine?
Early kidney damage often has no symptoms. That's why regular testing is important, especially for people with diabetes, high blood pressure, or a family history of kidney disease. Advanced proteinuria may cause foamy urine, swelling in legs, or fatigue.
How often should I have this test?
The frequency depends on your health condition. People with diabetes or known kidney disease may need testing every 3-6 months. Your healthcare provider will recommend an appropriate testing schedule based on your individual needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy