4ohxylazineurqlcfm
This test checks for the presence of 4-hydroxy xylazine, a breakdown product of xylazine, in your urine sample.
{"Detects exposure to xylazine, a veterinary sedative sometimes abused by humans","Uses a confirmatory method for accurate results","Commonly used in drug testing and forensic analysis"}
Key facts at a glance
- LOINC
- 103639-1
- Short code
- 4-OH-XYL-UR
- Synonyms
- 4OH-Xylazine Ur Ql Cfm
- Category
- chemistry
- Sample
- urine
- Container
- Sterile polypropylene urine collection cup with leak-proof lid
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 13 years
- Method
- confirm
- CPT
- 80307
- SNOMED
- 721066008
- Specimen volume
- Minimum 10 mL, preferred 20-50 mL
- Stability
- Room temperature (20-25°C): 5-7 days; Refrigerated (2-8°C): 2-4 weeks; Frozen (-20°C or below): 30+ days. Protect from light.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
What is this test?
This test looks for 4-hydroxy xylazine in your urine. 4-hydroxy xylazine is a metabolite, meaning it is what your body produces when it breaks down xylazine. Xylazine is a medication originally designed for use in animals as a sedative and pain reliever. However, it has been increasingly found in illicit drug supplies and may be used by humans, sometimes without their knowledge.
How is this test performed?
A urine sample is collected and sent to a laboratory for analysis. This test uses a confirmatory method, which is a highly accurate testing technique that can definitively identify the presence of 4-hydroxy xylazine. Unlike screening tests, confirmatory methods are more specific and reliable.
Why might I need this test?
Your healthcare provider may order this test if they suspect you have been exposed to xylazine. This could be part of a routine drug screening, an investigation of unexplained symptoms, or in legal/forensic situations. Xylazine use can cause serious health effects including drowsiness, slow heart rate, low blood pressure, and in severe cases, skin wounds or death.
What do the results mean?
A 'positive' result means that 4-hydroxy xylazine was detected in your urine, indicating recent exposure to xylazine. A 'negative' result means no 4-hydroxy xylazine was detected. It is important to discuss your results with your healthcare provider, who can explain what they mean for your specific situation.
Reference range
Not Detected - Negative result indicates absence of 4-hydroxy Xylazine metabolite in urine at the detection thresholdN/A
No special preparation required. Patient should provide a clean-catch urine sample. Inform laboratory of any medications or substances recently consumed. Avoid excessive fluid intake before collection as it may dilute the specimen.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
How long does xylazine stay in my urine?
Is this test part of standard drug screens?
What are the health risks of xylazine exposure?
Can I test positive from accidental exposure?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy