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6mamfreetisscoqlscn

Published: August 9, 2026Updated: August 10, 2026

This test checks if a newborn was exposed to heroin during pregnancy by testing the umbilical cord tissue.

Quick summary

{"Detects 6-monoacetylmorphine (6-MAM), a heroin breakdown product","Uses umbilical cord tissue as the sample, not blood or urine","Results show whether heroin was used during pregnancy","Used for newborn safety assessment and child protection","A positive result does not mean the baby is currently in danger"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
97210-9
Short code
6MAM-CORD
Synonyms
6MAM Free TissCo Ql Scn
Category
chemistry
Sample
serum
Container
Lavender top (EDTA) tube or sterile container for cord tissue
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
screen
CPT
80307
SNOMED
122465009
Specimen volume
1-2 mL cord blood or 5-10 g cord tissue
Stability
Refrigerated (2-8°C) for up to 7 days; frozen (-20°C) for longer storage
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

This test looks for 6-monoacetylmorphine (6-MAM) in the umbilical cord tissue. 6-MAM is a special substance that only appears when the body breaks down heroin. It is a marker that shows if a mother used heroin while pregnant.

Why is cord tissue used instead of blood or urine?

Umbilical cord tissue can show drug exposure over a longer period—approximately the last trimester of pregnancy. Blood or urine only show recent use (hours to days). Cord tissue testing is also less invasive and provides a longer detection window.

How is the test done?

After birth, a small piece of the umbilical cord is collected and sent to a laboratory. The tissue is analyzed using screening methods to detect the presence or absence of 6-MAM. The result is reported as 'Present' or 'Not Present'.

Reference range

Negative - No 6-monoacetylmorphine detectedN/A

Specimen: serum

No special preparation required. Collect cord blood/tissue at time of delivery.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Will a positive test affect my parental rights?
This test is used to help healthcare teams provide appropriate care for the baby. Results may be shared with child protective services as required by law. The goal is to ensure the baby receives proper medical care and support.
Can secondhand exposure cause a positive result?
It is unlikely that casual contact or secondhand exposure to heroin would cause a positive result in cord tissue testing, as the test detects actual heroin use by the mother.
What happens if the test is positive?
If positive, the newborn will be monitored for signs of neonatal abstinence syndrome (NAS), which includes symptoms like irritability, feeding difficulties, and sleep problems. Healthcare providers will develop an appropriate care plan for the baby.
How long does heroin stay detectable in cord tissue?
Cord tissue can detect drug exposure over approximately the last trimester (about 3 months) before birth. It provides a longer detection window compared to blood or urine tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy