Aabtitrserplahg
This test measures the amount (titer) of antibodies in your blood using the antihuman globulin method.
{"Measures the strength of antibodies in your blood","Helps diagnose conditions like autoimmune hemolytic anemia","Used before blood transfusions and during pregnancy","Involves mixing your blood with red blood cells","Results help doctors determine if treatment is needed"}
Key facts at a glance
- LOINC
- 38358-8
- Short code
- A Ab Titr SerPl AHG
- Synonyms
- A Ab Titr SerPl AHG
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- antihuman-globulin
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
The Antibody Titer test measures how many antibodies are present in your blood serum. Antibodies are proteins made by your immune system to fight off foreign substances like bacteria, viruses, or incompatible blood cells. The 'antihuman globulin' part refers to the Coombs test method used to detect these antibodies.
Why do I need this test?
Your doctor may order this test for several reasons: to check for hemolytic disease of the newborn if you are pregnant, to screen before a blood transfusion, to diagnose autoimmune hemolytic anemia (a condition where your body attacks its own red blood cells), or to monitor certain conditions that affect the immune system.
How is the test done?
A healthcare professional will draw a blood sample from a vein in your arm. The blood is then sent to a laboratory where technicians mix it with red blood cells and add antihuman globulin (Coombs reagent). If antibodies are present, they will clump together (agglutinate), and the lab can measure how much antibody is needed to cause this reaction.
What do the results mean?
A positive result means antibodies were detected in your blood. The titer (strength) helps your doctor understand how significant the antibody level is. A higher titer usually means more antibodies are present. Your doctor will interpret these results based on your specific health situation and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Does this test require fasting?
Are there any risks from this test?
How long does it take to get results?
What happens if my antibody titer is high?
Sources
- 1
- 2
- 3LabCorp - Antibody TiterSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy