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Alanine Aminotransferase (ALT) and Immunoglobulin G (IgG), Serum

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures ALT, a liver enzyme, along with IgG, an antibody involved in immune defense.

Quick summary

["This test helps assess liver-cell activity and the body's antibody or inflammatory response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
110026-2
Short code
A alternata IgG Msmt Ser
Synonyms
A alternata IgG Msmt Ser
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures two substances in serum, the liquid portion of blood. Alanine aminotransferase (ALT) is an enzyme that can rise when liver cells are injured, while immunoglobulin G (IgG) is a type of antibody that supports immune defense.

Why might I need this test?

A clinician may use these results when evaluating suspected liver disease, medication effects, or an unexplained illness. Measuring IgG can also provide information about chronic inflammation, infection, or immune-related conditions.

How is the test performed?

A blood sample is usually collected from a vein and sent to a laboratory. The laboratory separates the serum and analyzes it using standardized laboratory methods to determine the ALT and IgG concentrations.

How do I prepare for the test?

This test generally requires no special preparation. Follow your clinician's instructions, and tell the laboratory about medicines or supplements you take because some can affect liver-enzyme or IgG results.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ALT and IgG

Frequently asked questions

Do I need to fast for this test?
Fasting is usually not required unless your clinician specifically requests it or you are also having other tests that require fasting.
Can medicines affect the results?
Yes. Some medicines and supplements can affect ALT, while immune-modifying medicines and conditions that alter antibody production can affect IgG. Do not stop prescribed medicines without medical advice.
Does one abnormal result confirm a specific disease?
No. ALT and IgG must be interpreted with your symptoms, examination, medical history, and other tests because abnormal values are not specific to one condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy