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Abnprotmfrurelph

Published: August 9, 2026Updated: August 16, 2026

This test analyzes the proteins in your urine to detect abnormal protein bands that may indicate kidney problems or blood cell disorders.

Quick summary

{"A simple urine test that separates and identifies different protein types","Helps diagnose conditions like multiple myeloma and kidney disease","Results show if abnormal proteins are present in your urine","No special preparation is needed beyond collecting a clean urine sample","Abnormal results may require additional testing to determine the cause"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50408-4
Short code
UPEP
Synonyms
Abn Prot MFr Ur Elph
Category
chemistry
Sample
urine
Container
Clean-catch urine container, sterile polypropylene container
Units
N/A
Ref low
0
Ref high
100
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
electrophoresis
CPT
82044
SNOMED
314632009
Specimen volume
10-50 mL of urine
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): 2 weeks. Avoid repeated freeze-thaw cycles.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
48–96 hours
Order
routine

What is this test?

Urine protein electrophoresis (UPEP) is a laboratory test that separates the different proteins in your urine to identify abnormal protein bands. Normally, urine contains very small amounts of protein. When abnormal proteins or increased amounts of protein are found in urine, it may indicate an underlying health condition. The test uses an electrical current to separate proteins based on their size and electrical charge, creating a pattern that healthcare providers can analyze.

Why is it ordered?

This test is typically ordered when a routine urine test shows high protein levels (proteinuria). It helps determine the source and type of protein causing the abnormality. The test is particularly useful for detecting proteins produced by abnormal plasma cells, such as in multiple myeloma, or for identifying kidney disorders that affect protein filtration.

How is it performed?

You will provide a urine sample, usually collected in a sterile container. For the most accurate results, a first-morning sample is often preferred as it is more concentrated. The laboratory then applies the urine to a special gel and applies an electrical current to separate the proteins. The resulting pattern is compared to normal patterns to identify any abnormal bands.

Reference range

Normal: <100 pg/mLN/A

Specimen: urine

No fasting required. Collect a clean-catch, midstream urine sample. Inform patient to avoid strenuous exercise 24 hours before collection as this may cause transient proteinuria. Collect first morning specimen preferred for most accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Does this test hurt?
No, urine collection is painless. You simply urinate into a sterile container provided by the laboratory or your healthcare provider's office.
Do I need to fast before the test?
No fasting is typically required for this test. However, follow any specific instructions provided by your healthcare provider.
How long does it take to get results?
Results are usually available within a few days, as the test requires specialized laboratory processing and analysis.
What does it mean if I have protein in my urine?
Small amounts of protein in urine can be normal, especially after exercise or illness. Persistent protein in urine (proteinuria) may indicate kidney problems or other conditions that require further investigation. Your healthcare provider will interpret your results based on your overall health and other test findings.
Will I need additional tests if my results are abnormal?
If abnormal protein bands are detected, your healthcare provider may order additional tests such as blood protein electrophoresis, immunofixation studies, or imaging tests to determine the cause and guide treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy