Complete Blood Count (CBC): What This Blood Test Measures and Why Your Doctor May Order It
This test measures the activity or amount of an enzyme called acetyl-CoA:glucosamine acetyltransferase in white blood cells, which helps assess certain metabolic and genetic conditions.
{"Measures enzyme activity in white blood cells (leukocytes)","Helps evaluate metabolic and genetic conditions affecting enzyme function","Requires a blood sample (serum)","Results are reported as enzymatic activity or mass","Your healthcare provider will interpret results based on your specific situation"}
Key facts at a glance
- LOINC
- 24044-0
- Short code
- ACGAT
- Synonyms
- AcCoA:Glucosamine AT WBC-cCnt
- Category
- chemistry
- Sample
- serum
- Container
- Red top serum separator tube (SST) or plain red top tube
- Units
- N/A
- Ref low
- 4.5
- Ref high
- 11
- Critical range
- 2 N/A – 30 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Spectrophotometric enzymatic assay
- CPT
- 85004
- SNOMED
- 314215002
- Specimen volume
- 2-5 mL venous blood
- Stability
- Process specimen within 2-4 hours of collection. Store at 2-8°C if delay exceeds 4 hours. Avoid freezing whole blood.
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 20
- TAT
- 48–168 hours
- Order
- routine
The complete blood count, or CBC, is a routine blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. It gives your doctor a broad picture of your overall health and helps detect many different conditions.
The acetyl-CoA:glucosamine acetyltransferase test measures the levels or activity of a specific enzyme in your white blood cells (leukocytes). This enzyme, also known as glucosamine-6-phosphate N-acetyltransferase, plays an important role in the hexosamine biosynthetic pathway, which is involved in how your cells process certain sugars and produce energy.
This test is performed to look for problems such as anemia, infections, and blood disorders. It is often included in a regular health checkup, or it may be ordered to investigate symptoms like fatigue, weakness, fever, bruising, or unusual bleeding, and to monitor how a treatment is working.
This test is typically ordered to help diagnose or monitor certain metabolic disorders, genetic conditions, or diseases that may affect enzyme function. It may be used when a healthcare provider suspects there is a problem with how the body processes certain nutrients or produces cellular energy.
The test is done with a simple blood draw. A healthcare provider cleans a spot on your arm, usually the inside of the elbow, ties a band around your upper arm, and collects a small sample of blood into a tube. The sample is then sent to a laboratory for analysis, and the whole process usually takes only a few minutes.
A healthcare professional will collect a blood sample from a vein in your arm. The sample is then sent to a laboratory where specialists isolate the white blood cells and measure the enzyme activity or mass. The procedure is quick and similar to routine blood tests.
This test is very safe. You may feel a quick sting when the needle goes in, and some people notice mild soreness, bruising, or a small amount of bleeding at the puncture site afterward. Serious problems, such as infection or heavy bleeding, are rare. Tell your provider if you take blood thinners or have a bleeding disorder.
The risks are minimal and similar to any standard blood draw, including slight bruising, bleeding, or rare chance of infection at the puncture site. Some people may feel lightheaded during or after the blood draw.
Reference range
Adult: 4.5-11.0 x 10^9/LN/A
No special preparation required. Standard venipuncture procedure. Avoid hemolysis during collection and processing as it may affect leukocyte integrity.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal levels of acetyl-CoA:glucosamine acetyltransferase may indicate certain metabolic disorders, genetic conditions affecting enzyme production, or other health issues. Your doctor will interpret the results alongside your symptoms, medical history, and other test results to determine the next steps. This test is specialized and is typically ordered by specialists familiar with metabolic or genetic conditions.
Frequently asked questions
Do I need to fast before this test?
How long does it take to get results?
What do abnormal results mean?
Will I need additional tests?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy