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Acenocoumarolfldmcnc

Published: August 9, 2026Updated: August 10, 2026

This test measures the amount of acenocoumarol, an anticoagulant medication, in your blood to ensure you are receiving the correct dose.

Quick summary

{"Acenocoumarol is a blood-thinning medication used to prevent blood clots","Regular monitoring helps maintain therapeutic effectiveness while reducing bleeding risk","Blood samples are typically collected from a vein in your arm"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
79152-5
Short code
ACEN
Synonyms
Acenocoumarol Fld-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST, gold top) or plain red top tube. Avoid heparinized tubes as they may interfere with some assays.
Units
N/A
Ref low
0.5
Ref high
2
Critical range
0.2 N/A – 4 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or High-Performance Liquid Chromatography (HPLC) with UV detection
CPT
80299 (Therapeutic drug monitoring; not otherwise specified) or 82491 (Chromatographic assay, therapeutic drug, quantitative)
SNOMED
424573004 (Acenocoumarol measurement) or 373499006 (Anticoagulant therapy)
Specimen volume
2-5 mL of serum minimum
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C or below): 30 days. Protect from light as acenocoumarol is light-sensitive.
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

The acenocoumarol test measures the concentration of acenocoumarol in your blood serum. Acenocoumarol is an oral anticoagulant (blood thinner) belonging to the vitamin K antagonist class. This medication is prescribed to prevent and treat blood clots in conditions such as deep vein thrombosis, pulmonary embolism, and certain heart conditions like atrial fibrillation.

How is the test performed?

A healthcare professional will draw a blood sample from a vein in your arm. The sample is then sent to a laboratory where the concentration of acenocoumarol is measured. The results help your doctor determine if your current dosage is appropriate.

Reference range

Therapeutic range: 0.5-2.0 mcg/mL (50-200 ng/mL). Target INR range: 2.0-3.5 for most indications. Reference range may vary based on indication and individual patient factors. Consult with prescribing physician for patient-specific target range.N/A

Specimen: serum

Collect specimen as trough level, just before next scheduled dose. Inform laboratory of dose timing. Report any recent dose adjustments, missed doses, or changes in medications. Notify of any bleeding, bruising, or signs of thrombosis. Maintain consistent dietary vitamin K intake.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need this test?
Your doctor needs to check if your acenocoumarol dose is correct. The right dose prevents dangerous blood clots without causing excessive bleeding.
How often should I have this test?
Testing frequency depends on your condition and stability. Initially, tests may be done weekly, then monthly once your dose is stable. Your doctor will determine the appropriate schedule for you.
Does this test require fasting?
Typically, no fasting is required for this test. However, follow any specific instructions provided by your healthcare provider.
What if my acenocoumarol level is too high?
A high level may indicate risk of bleeding. Your doctor may lower your dose or recommend temporary discontinuation. Contact your healthcare provider immediately if you notice unusual bruising, bleeding, or bloody stools.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy