Prothrombin Time (PT/INR) Test for Acenocoumarol Monitoring
This test measures the amount of acenocoumarol, an anticoagulant medication, in your blood to ensure proper dosing and prevent complications.
{"Acenocoumarol is a blood-thinning medication that prevents dangerous blood clots","Regular monitoring ensures the drug is working effectively and safely","The test helps maintain your INR within the therapeutic range","Proper levels reduce risk of both bleeding and clotting complications","Test frequency depends on your condition and stability of readings"}
Key facts at a glance
- LOINC
- 35102-3
- Short code
- ACEN
- Synonyms
- Acenocoumarol SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or EDTA plasma tube
- Units
- N/A
- Ref low
- 0.5
- Ref high
- 2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or High-Performance Liquid Chromatography (HPLC)
- CPT
- 80299
- SNOMED
- 385058006
- Specimen volume
- 2-5 mL of serum or plasma
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Protect from light.
- Hemolysis max
- 50
- Lipemia max
- 300
- Icterus max
- 20
- TAT
- 24–72 hours
- Order
- routine
This is a blood test that measures how long it takes your blood to clot. It is reported as a prothrombin time (PT) and an international normalized ratio (INR), a standardized value that helps your doctor determine whether your blood is clotting too quickly or too slowly while you take acenocoumarol.
The acenocoumarol blood test measures the concentration of acenocoumarol in your serum or plasma. Acenocoumarol is an anticoagulant (blood thinner) medication that belongs to a class of drugs called vitamin K antagonists. This test is a type of therapeutic drug monitoring, which means it checks whether the amount of medication in your blood is within the optimal range for preventing blood clots while minimizing the risk of bleeding complications.
This test is performed to monitor the effect of acenocoumarol, an anticoagulant (blood thinner), so your doctor can adjust your dose safely. The goal is to keep your INR within a target range that prevents harmful blood clots without causing excessive or unexpected bleeding.
Your healthcare provider orders this test to monitor your response to acenocoumarol therapy. The goal is to maintain what's called a therapeutic range, which is typically measured by your INR (International Normalized Ratio). If your acenocoumarol level is too low, you may be at risk for developing blood clots. If it's too high, you may be at risk for excessive bleeding. Regular testing helps your doctor adjust your dosage to find the right balance for your specific situation.
Acenocoumarol is used to prevent and treat conditions involving abnormal blood clot formation, including deep vein thrombosis, pulmonary embolism, atrial fibrillation, and clot risk associated with mechanical heart valves. Regular INR testing helps ensure the medication works correctly for these conditions.
Acenocoumarol is prescribed to prevent and treat blood clots in conditions such as atrial fibrillation (irregular heart rhythm), deep vein thrombosis (DVT), pulmonary embolism, heart valve replacement, and certain types of stroke prevention. It is commonly used in many countries outside the United States, where warfarin is more frequently prescribed.
The test is performed by drawing a small sample of blood from a vein in your arm, usually from the inside of the elbow or the back of the hand. The sample is sent to a laboratory, where the PT and INR are measured. The procedure takes only a few minutes, and you can resume normal activities afterward.
A healthcare professional will draw a small blood sample from a vein in your arm. The sample is then sent to a laboratory for analysis. The results are typically reported as a concentration (mass/volume) in your serum or plasma. Your doctor will interpret these results along with your INR values to determine if your current dosage is appropriate.
Reference range
Therapeutic range: 0.5-2.0 mcg/mL. Target INR range for acenocoumarol therapy is typically 2.0-3.0. Drug concentrations should be interpreted in conjunction with INR results and clinical context.N/A
Collect sample immediately before next scheduled dose (trough level) for accurate therapeutic drug monitoring. Inform laboratory of dose timing and last intake. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings2
Frequently asked questions
What is a therapeutic INR range?
How often do I need this test?
What can affect my acenocoumarol levels?
What should I do if my levels are too high or too low?
Do I need to fast before this test?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy