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Acepromazinedose

Published: August 9, 2026Updated: August 15, 2026

This test measures the concentration of acepromazine, a sedative medication, in your animal's blood to ensure proper dosing and safety.

Quick summary

{"Acepromazine is a sedative used in veterinary medicine for horses and companion animals","This test measures drug levels in blood serum to monitor therapy","Helps veterinarians ensure safe and effective dosing","Sample is collected via blood draw","Results help adjust dosage or check for toxicity"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
4104-6
Short code
ACEPMZ
Synonyms
Acepromazine Dose
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red top serum tube
Units
N/A
Ref low
10
Ref high
50
Critical range
— – 150 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
80307
SNOMED
373497006
Specimen volume
1.0 mL serum minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

The Acepromazine Blood Level Test measures the amount of acepromazine in your animal's blood serum. Acepromazine (also called acetylpromazine) is a phenothiazine-based sedative and tranquilizer commonly used in veterinary medicine to calm animals during procedures, treat anxiety, or manage motion sickness. This test helps veterinarians determine if the drug is present at therapeutic levels or if the dose needs adjustment.

Why is this test performed?

Veterinarians may order this test for several reasons: to monitor drug levels in animals receiving acepromazine therapy, to ensure the dosage is appropriate for effective sedation, to check for potential drug accumulation or toxicity, and to verify compliance with treatment protocols. It is particularly important for animals on long-term therapy or those with conditions that may affect drug metabolism.

How is the test performed?

A small blood sample is drawn from your animal's vein, typically from the jugular vein in horses or from a leg vein in dogs and cats. The sample is then placed in a special tube to separate the serum (the liquid part of blood). The serum is analyzed in a laboratory using specialized equipment to measure the acepromazine concentration. The procedure is quick and generally well-tolerated by animals.

What do the results mean?

Results are reported as mass of acepromazine per volume of serum. Your veterinarian will interpret the results based on your animal's specific situation, including the dose given, time since administration, and the reason for testing. Therapeutic drug monitoring helps ensure the drug is working effectively while minimizing the risk of side effects. If levels are too low, the dose may be increased; if levels are too high, the dose may be reduced or discontinued.

Reference range

Therapeutic range: 10-50 ng/mL; Toxic level: >100 ng/mL. Reference ranges may vary by species and clinical indication.N/A

Specimen: serum

No specific preparation required. Collect sample via venipuncture into serum separator tube. Allow tube to clot for 30 minutes at room temperature before centrifugation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is acepromazine safe for all animals?
Acepromazine is generally safe when used appropriately, but it should be used with caution in animals with liver disease, heart conditions, or dehydration. It is not recommended for use in pregnant animals or young foals. Your veterinarian will assess your animal's health status before prescribing this medication.
How long does it take to get results?
turnaround time varies by laboratory but typically takes 1-3 days. The test requires specialized equipment and expertise, so not all veterinary clinics can perform it in-house.
Are there any side effects of acepromazine?
Common side effects may include drowsiness, drooling, and temporary loss of coordination. In horses, a temporary protrusion of the third eyelid (nictitating membrane) may occur. Rare but serious side effects include low blood pressure, excitement, and in horses, penile prolapse. Contact your veterinarian if you notice any concerning symptoms.
Does my animal need to fast before the test?
Your veterinarian will provide specific instructions. Fasting is not typically required for this blood test, but always follow your veterinarian's pre-test instructions to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy