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Acetateairmcnc

Published: August 9, 2026Updated: August 16, 2026

This test measures acetate levels in exhaled air to help evaluate metabolic function and certain metabolic disorders.

Quick summary

{"Measures acetate (a type of acid) in breath samples","Helps diagnose and monitor metabolic disorders","Involved in conditions like diabetic ketoacidosis","Non-invasive breath test procedure","Results help doctors assess how your body processes fats"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38658-1
Short code
ACE air
Synonyms
Acetate Air-mCnc
Category
chemistry
Sample
serum
Container
specialized breath collection container or Tedlar bag
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
gas chromatography-mass spectrometry (GC-MS) or enzymatic assay
CPT
82803
SNOMED
44703009
Specimen volume
minimum 100 mL breath sample or as specified by collection device
Stability
analyze within 24 hours; store at 2-8°C if delay exceeds 4 hours
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–72 hours
Order
routine

What is this test?

The acetate test measures the amount of acetate, a type of volatile organic compound, in your exhaled breath or air sample. Acetate is a byproduct of fat metabolism and is normally produced in small amounts by the body. When metabolic processes are disrupted, acetate levels can change significantly.

Why is it performed?

This test is typically ordered to help evaluate metabolic function, particularly in conditions affecting fat metabolism. It may be used to monitor conditions such as diabetic ketoacidosis, certain liver disorders, or inborn errors of metabolism. The test can also be helpful in assessing the effectiveness of treatments for these conditions.

How is the sample collected?

For this test, you will be asked to exhale into a special collection device or bag. The sample is then analyzed in a laboratory to measure the acetate concentration. The procedure is non-invasive and typically takes only a few minutes. You may be asked to fast or avoid certain foods before the test, depending on your doctor's instructions.

Understanding your results

Normal acetate levels in breath vary depending on the laboratory and method used. Your doctor will interpret your results based on your overall health, symptoms, and other test findings. Elevated acetate levels may indicate metabolic disturbances, while very low levels are less common but can also provide important clinical information.

Reference range

Reference range not well established; consult laboratory for interpretationN/A

Specimen: serum

Patient should fast for at least 8 hours prior to collection. Avoid alcohol and nicotine for 24 hours before testing. Avoid high-fat meals the evening before collection. Inform laboratory of any medications that may affect acetate metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Do I need to prepare for this test?
Your doctor may ask you to fast for a certain period before the test, typically 8-12 hours. Avoid alcohol, smoking, and strenuous exercise before the test as these can affect results. Follow any specific instructions provided by your healthcare provider.
Is the test painful?
No, this is a non-invasive test. You simply breathe into a collection device. There is no needle or discomfort involved.
How long does it take to get results?
Results are typically available within 1-3 days, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
What do high acetate levels mean?
High acetate levels in breath may indicate increased fat metabolism, which can occur in diabetic ketoacidosis, prolonged fasting, very low-carb diets, or certain metabolic disorders. Your doctor will interpret these results in the context of your overall health and other test results.
Can I take my medications before the test?
Inform your doctor about all medications you are taking. Some medications may affect metabolic processes and potentially influence test results. Do not stop prescribed medications unless specifically instructed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy