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Acetonefldmcnc

Published: August 9, 2026Updated: August 15, 2026

This test measures the level of acetone (a type of ketone body) in your blood or other body fluids.

Quick summary

{"Measures acetone levels in serum or body fluids","Helps diagnose and monitor diabetic ketoacidosis (DKA)","Used to evaluate metabolic disorders and fasting states","Results indicate how well your body is using fat for energy","Abnormal levels may require immediate medical attention"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
16311-3
Short code
ACET
Synonyms
Acetone Fld-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
0
Ref high
1
Critical range
— – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Enzymatic
CPT
80378
SNOMED
414568004
Specimen volume
1.0-2.0 mL serum minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
2–24 hours
Order
routine

What is this test?

The Acetone test measures the amount of acetone, a ketone body, in your blood serum or other body fluids. Ketone bodies are produced when your body breaks down fat for energy instead of using glucose. This test helps healthcare providers understand how your body is metabolizing energy.

Why is this test performed?

Your doctor may order this test if you have diabetes and are at risk for diabetic ketoacidosis (DKA), a serious condition where high ketone levels make your blood too acidic. It may also be used to monitor people on ketogenic diets, those fasting for extended periods, or patients with certain metabolic disorders.

How is the test done?

A healthcare professional will draw a blood sample from a vein in your arm. The sample is then sent to a laboratory for analysis. No special preparation is usually required, but follow your doctor's instructions regarding fasting or medication adjustments before the test.

What do the results mean?

Normal acetone levels are typically very low or undetectable. Elevated levels may indicate diabetic ketoacidosis, prolonged fasting, a very low-carbohydrate diet, alcoholism, or certain metabolic disorders. Your doctor will interpret your results in context with your overall health and other test findings.

Reference range

Negative or <1.0 mg/dL (<0.17 mmol/L)N/A

Specimen: serum

No special preparation required. Patient may fast overnight for accurate ketone body assessment. Avoid alcohol consumption for 24 hours before specimen collection. Inform physician of any medications including insulin, metformin, or sodium bicarbonate

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is fasting required before the test?
Follow your healthcare provider's instructions. Some tests may require fasting, while others do not. Always inform your doctor about any medications or supplements you're taking.
What are the symptoms of high ketone levels?
Symptoms may include excessive thirst, frequent urination, nausea, vomiting, abdominal pain, confusion, fruity-smelling breath, and rapid breathing. Seek immediate medical attention if you experience these symptoms, especially if you have diabetes.
How is high acetone treated?
Treatment depends on the underlying cause. For diabetic ketoacidosis, treatment typically includes insulin therapy, intravenous fluids, and electrolyte replacement. Always follow your healthcare provider's treatment plan.
Can diet affect my acetone levels?
Yes, very low-carbohydrate diets (ketogenic diets), prolonged fasting, or strict calorie restriction can increase ketone and acetone levels. This is usually normal but should be monitored by a healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy