Understanding Your Laboratory Test: What It Is, How It Is Done, and Why You May Need It
This test detects the presence of acetone, a type of ketone body, in stomach fluid to help diagnose metabolic conditions.
{"Acetone in gastric fluid indicates the body is producing excess ketones, often due to diabetes or fasting","The test helps doctors identify diabetic ketoacidosis and other metabolic disorders","Sample is collected through gastric aspiration (stomach tube) or vomit specimen"}
Key facts at a glance
- LOINC
- 40598-5
- Short code
- ACET-GF
- Synonyms
- Acetone Gast Ql
- Category
- chemistry
- Sample
- serum
- Container
- Sterile container (glass or plastic) for gastric fluid collection; red-top or gray-top serum tube if serum sample is collected
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Chemical reaction / Colorimetric assay
- CPT
- 80307
- SNOMED
- 271252004
- Specimen volume
- Gastric fluid: 2-5 mL preferred; Serum: 1-2 mL minimum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): 2 weeks. Avoid prolonged exposure to air.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
This test is a laboratory analysis that helps your healthcare provider learn more about what is happening inside your body. It may measure substances in your blood, urine, or other samples to check how well your organs are working, screen for certain conditions, or monitor treatment you are already receiving. Your provider will explain what the results mean in the context of your symptoms and overall health.
The Acetone in Gastric Fluid test detects whether acetone, a ketone body produced when the body breaks down fat for energy, is present in stomach contents. Normally, the stomach should not contain significant amounts of acetone. When detected, it typically indicates an underlying metabolic condition that requires medical attention.
Sample collection depends on the type of test your provider orders. Most commonly, a trained phlebotomist draws a small amount of blood from a vein in your arm using a thin needle, which takes only a few minutes. Some tests require a urine sample, a throat or nasal swab, or a saliva sample instead. You may receive specific instructions, such as fasting beforehand, and it is important to follow them carefully so the results are accurate.
The sample is collected through a procedure called gastric aspiration, where a thin tube is passed through the nose or mouth into the stomach to collect fluid. Alternatively, a vomit sample may be collected. The collected fluid is then sent to the laboratory for analysis.
Your healthcare provider may order this test for many reasons, including finding the cause of symptoms you are experiencing, routine screening for common conditions, monitoring a chronic illness such as diabetes or thyroid disease, or checking how well a medication is working. Early results can help detect problems before complications develop and guide decisions about your ongoing care and treatment plan.
Your doctor may order this test if you have symptoms of diabetic ketoacidosis (DKA), such as persistent vomiting, abdominal pain, rapid breathing, or confusion. It may also be used when evaluating patients with unexplained metabolic acidosis or those at risk for ketone body accumulation.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Inform the laboratory of any medications or supplements recently consumed. Provide clinical history regarding possible toxin exposure or diabetes management.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is the test painful?
How long does it take to get results?
What do positive results mean?
Do I need to fast before this test?
Is this test dangerous?
Sources
- 1
- 2MedlinePlus - KetonesSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy