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Acetonegastscnc

Published: August 9, 2026Updated: August 10, 2026

This test measures acetone levels in stomach fluid to help evaluate metabolic conditions, particularly diabetic ketoacidosis.

Quick summary

{"Measures acetone (a ketone body) concentration in gastric fluid","Helps diagnose and monitor diabetic ketoacidosis","Sample collected via endoscopy or nasogastric tube","Elevated levels may indicate serious metabolic imbalance","Results are interpreted in context with other clinical findings"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
59864-9
Short code
ACET-GF
Synonyms
Acetone Gast-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
0
Ref high
0.5
Critical range
— – 6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–100 years
Method
Enzymatic method using alcohol dehydrogenase or gas chromatography-mass spectrometry (GC-MS)
CPT
80378
SNOMED
413542009
Specimen volume
1.0-2.0 mL of serum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
50
Lipemia max
100
Icterus max
40
TAT
4–24 hours
Order
routine

What is this test?

The Gastric Fluid Acetone test measures the amount of acetone, a type of ketone body, in your stomach fluid. Acetone is produced when the body breaks down fat for energy, which typically happens when there is insufficient insulin to use glucose properly. This test helps healthcare providers evaluate your metabolic state, particularly if diabetes-related complications are suspected.

How is the test performed?

A small sample of gastric fluid is collected through either an endoscopy procedure (where a flexible tube with a camera is passed through the mouth into the stomach) or a nasogastric tube (a tube inserted through the nose into the stomach). The collected fluid is then sent to a laboratory where the acetone concentration is measured using specialized chemical analysis methods.

Why might I need this test?

Your doctor may order this test if you have symptoms of diabetic ketoacidosis (DKA), such as excessive thirst, frequent urination, nausea, vomiting, abdominal pain, confusion, or rapid breathing. It may also be used to monitor patients with poorly controlled diabetes or those at risk of developing metabolic complications. Additionally, this test can help evaluate unexplained metabolic acidosis or monitor the effectiveness of diabetes treatment.

What do the results mean?

Normal results typically show minimal or undetectable acetone in gastric fluid. Elevated levels may indicate diabetic ketoacidosis, prolonged fasting, extreme diets (such as ketogenic diet), or other conditions causing ketone body production. Your healthcare provider will interpret your results along with other clinical findings, blood tests, and your overall health condition to make an accurate diagnosis and determine appropriate treatment.

Are there any risks?

The risks associated with this test are minimal and primarily related to the sample collection method. Endoscopy may cause mild throat discomfort or rare complications like bleeding or perforation. Nasogastric tube insertion may cause minor nose or throat irritation. These procedures are generally safe when performed by trained healthcare professionals.

Reference range

Acetone is normally not detectable or present in very low concentrations (<0.5 mmol/L). Reference range may vary by laboratory methodology.N/A

Specimen: serum

No special preparation required. Inform laboratory of any medications, supplements, or recent alcohol consumption.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Your healthcare provider will provide specific instructions. In general, you may be asked to fast for several hours before the test, especially if the sample is collected via nasogastric tube. Follow your doctor's instructions carefully to ensure accurate results.
How long does it take to get results?
Results are typically available within 24-48 hours, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
What happens if my acetone levels are high?
Elevated acetone levels may indicate diabetic ketoacidosis, which requires immediate medical treatment. Your healthcare provider will determine the appropriate course of action, which may include insulin therapy, fluid replacement, and monitoring in a healthcare setting. Do not ignore abnormal results.
Can this test diagnose diabetes?
No, this test is not used to diagnose diabetes. It is used to monitor metabolic complications in people who already have diabetes, particularly to detect or monitor ketoacidosis. Blood glucose tests and other tests are used to diagnose diabetes.
Is the test painful?
The sample collection procedure may cause some discomfort, but it is generally well-tolerated. Endoscopy may cause a sore throat for a day or two afterward. The procedure is performed by experienced healthcare professionals to minimize discomfort.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy