Patient Guide to the General Health Assessment Test: What It Is, Why It Is Performed, and How to Prepare
A blood test that measures acetone levels to evaluate ketone production in the body.
{"Measures acetone, a type of ketone body, in blood","Used to diagnose and monitor diabetic ketoacidosis (DKA)","Helps assess metabolic conditions like ketosis","Sample collected via blood draw from vein","Results help doctors evaluate how your body is metabolizing fat"}
Key facts at a glance
- LOINC
- 109547-0
- Short code
- ACETB
- Synonyms
- Acetone Msmt Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- Gray-top tube (sodium fluoride/potassium oxalate) or purple-top tube (EDTA)
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Enzymatic assay (beta-hydroxybutyrate dehydrogenase) or gas chromatography-mass spectrometry (GC-MS)
- CPT
- 80378
- SNOMED
- 39854009
- Specimen volume
- 2-3 mL whole blood
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 50
- Lipemia max
- 300
- Icterus max
- 20
- TAT
- 24–72 hours
- Order
- routine
This test is a routine medical examination that allows your doctor to gather important information about your body's function and health status using safe and standardized methods.
The Blood Acetone test measures the amount of acetone, a type of ketone body, in your blood. Ketones are produced when your body breaks down fat for energy instead of using glucose. This test helps healthcare providers understand how your body is metabolizing fats and whether you have abnormal levels of ketones in your bloodstream.
Your healthcare provider may recommend this test to screen for potential health issues, monitor an ongoing condition, or evaluate how well a treatment plan is working for your specific needs.
This test is primarily ordered to help diagnose and monitor conditions associated with high ketone production. It is commonly used for patients with diabetes to check for diabetic ketoacidosis (DKA), a serious complication. The test may also be used to evaluate unexplained metabolic disturbances, monitor patients on ketogenic diets, or assess fasting states. Additionally, it can help differentiate between different causes of metabolic acidosis.
The test is performed by a trained professional who will collect the necessary sample or measurement in a comfortable setting, following strict hygiene and safety protocols to ensure accurate results.
A healthcare professional will draw a blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. The procedure is quick and typically takes only a few minutes. You may feel a slight sting when the needle is inserted or removed. There is minimal risk involved, though you might experience some bruising at the injection site.
To prepare for the test, you should follow any instructions given by your clinic, such as fasting if required, wearing loose clothing, and informing your provider about all medications you currently take.
Your doctor may ask you to fast for a certain period before the test, as eating can affect ketone levels. Inform your healthcare provider about any medications, supplements, or dietary changes you are experiencing. If you have diabetes, follow your doctor's instructions regarding insulin or medication use before the test. Always disclose your complete medical history to ensure accurate interpretation of results.
Reference range
Reference range: <1.0 mg/dL (<17.2 μmol/L) in whole blood. Results may vary by laboratory methodology.N/A
No special preparation required. Inform laboratory of recent meals, diabetes status, or ketogenic diet. Avoid alcohol consumption prior to collection as it may affect ketone body metabolism.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated blood acetone levels indicate increased ketone production, which may occur in diabetic ketoacidosis (DKA), prolonged fasting, alcoholism, or low-carbohydrate diets. High levels can lead to metabolic acidosis, a dangerous condition where the blood becomes too acidic. In diabetes management, monitoring acetone helps prevent DKA, a life-threatening complication. Low or normal acetone levels typically indicate normal fat metabolism. The test results, combined with other clinical findings, help doctors diagnose metabolic disorders and guide treatment decisions.
Frequently asked questions
What does it mean if my blood acetone is high?
Is fasting required before this test?
How long does it take to get results?
Can I do this test at home?
What conditions are associated with abnormal acetone levels?
Sources
- 1MedlinePlus - KetonesSource
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy