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Acrylfentanylurcfmmcnc

Published: August 9, 2026Updated: August 16, 2026

A confirmatory urine test that detects acrylfentanyl, a potent synthetic opioid, to identify drug exposure.

Quick summary

{"This test detects acrylfentanyl, a synthetic opioid much stronger than morphine","It uses urine sample to confirm acrylfentanyl exposure for clinical or forensic purposes","Acrylfentanyl is not a regulated pharmaceutical and is often abused recreationally","Positive results may indicate drug use and require clinical interpretation","The test helps healthcare providers assess exposure in emergency or monitoring situations"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93468-7
Short code
ACRYFU
Synonyms
Acrylfentanyl Ur Cfm-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container (clean catch)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
confirm
CPT
80307
SNOMED
8710006
Specimen volume
10-30 mL
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
48–168 hours
Order
routine

What is this test?

This test uses a confirmatory method (mass spectrometry) to detect acrylfentanyl and its metabolites in your urine. Acrylfentanyl (also called acryloylfentanyl) is a synthetic opioid analog of fentanyl. It is classified as a new psychoactive substance (NPS) and is not approved for medical use in most countries. The test is highly specific and accurate for identifying acrylfentanyl exposure.

How is the test performed?

A urine sample is collected in a sterile container. The sample is then analyzed in a laboratory using mass spectrometry techniques, which can identify even small amounts of acrylfentanyl or its metabolites. This confirmatory method is more accurate than initial screening tests.

Why might I need this test?

Your healthcare provider may order this test if: you show symptoms of opioid overdose or poisoning, there is suspicion of synthetic opioid exposure, you are in a drug monitoring program, or for forensic/legal purposes. It may also be used in emergency situations when standard opioid tests are negative but clinical symptoms suggest opioid use.

Reference range

Not Detected (Cutoff: 0.5 ng/mL)N/A

Specimen: urine

Patient should provide a clean catch urine specimen. Avoid excessive fluid intake before collection that may dilute the specimen. Inform patient of controlled substance testing and obtain appropriate consent. Collection should be observed or documented to prevent adulteration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is acrylfentanyl the same as fentanyl?
No, acrylfentanyl is a different synthetic opioid that is chemically related to fentanyl but has a slightly different structure. Both are extremely potent, but acrylfentanyl is not approved for medical use and is often produced illegally.
How long does acrylfentanyl stay in urine?
Acrylfentanyl and its metabolites can typically be detected in urine for 2-4 days after use, depending on factors such as dosage, frequency of use, metabolism, and kidney function.
Will this test show if I am addicted?
This test detects exposure but cannot determine addiction or level of impairment. It is a tool to help healthcare providers understand what substances may be present in your body.
Do I need to prepare for this test?
No special preparation is needed. Simply provide a clean urine sample as instructed by your healthcare provider or collection site.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy