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Acylcarnitinedbsscnc

Published: August 9, 2026Updated: August 16, 2026

Acylcarnitine testing measures specific fatty acid compounds in the blood to help detect metabolic disorders.

Quick summary

{"Acylcarnitine test helps diagnose disorders affecting how the body converts fat to energy","It is commonly used in newborn screening but can be performed at any age","Abnormal results may indicate genetic metabolic conditions requiring treatment","The test uses a blood sample, typically from a finger prick or heel stick","Early detection allows for better management of metabolic disorders"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38474-3
Short code
Acylcarnitine DBS-sCnc
Synonyms
Acylcarnitine DBS-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The acylcarnitine test measures the levels of acylcarnitine compounds in your blood. Acylcarnitines are substances that help transport fatty acids into the mitochondria, the energy-producing parts of your cells. This test helps doctors evaluate how well your body processes fats for energy.

Why is this test performed?

This test is primarily used to screen for and diagnose metabolic disorders, particularly fatty acid oxidation disorders and organic acidemias. These are genetic conditions where the body cannot properly break down fats or certain proteins for energy. The test is commonly performed on newborns as part of routine screening programs, but it may also be ordered for children or adults experiencing symptoms such as fatigue, muscle weakness, or low blood sugar.

How is the test done?

A healthcare professional will collect a blood sample, usually from a vein in your arm or from a finger prick. For newborn screening, a small blood sample is typically taken from the baby's heel. The blood is then sent to a laboratory where specialists measure the levels of different acylcarnitine compounds. The test requires fasting, typically for 8-12 hours before the blood draw, as this helps provide accurate results.

Are there any risks?

The risks associated with this test are minimal and similar to routine blood tests. You may experience slight pain or bruising at the puncture site. Some people may feel dizzy or lightheaded during or after the blood draw. These side effects are usually temporary and resolve quickly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to prepare for the test?
Yes, you will typically need to fast for 8-12 hours before the test. Your doctor may provide specific instructions. It is important to follow these guidelines carefully, as eating can affect the test results. You may drink water during the fasting period.
How long does it take to get results?
Results are usually available within a few days to a week, depending on the laboratory. For newborn screening, results may take slightly longer as the sample often goes to a specialized newborn screening laboratory. Your healthcare provider will contact you with the results.
What do abnormal results mean?
Abnormal results do not always mean your baby or you have a metabolic disorder. Sometimes results can be slightly abnormal due to other factors. If results are abnormal, your doctor will typically recommend additional testing to confirm a diagnosis. It is important to follow up with your healthcare provider to discuss any abnormal results and next steps.
Is this test only for newborns?
No, while commonly performed as part of newborn screening, this test can be ordered for individuals of any age when metabolic disorders are suspected. Older children or adults may be tested if they show symptoms such as recurring episodes of vomiting, lethargy, low blood sugar, or muscle problems.
  1. 1
    MedlinePlus - AcylcarnitineSource
  2. 2
    Mayo Clinic Laboratories - Acylcarnitine ProfileSource
  3. 3
    Children's National Hospital - Newborn ScreeningSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy