Skip to content

Acylcarnitinescserplscnc

Published: August 9, 2026Updated: August 15, 2026

This blood test measures the levels of short-chain acylcarnitine in your blood to help diagnose certain metabolic disorders.

Quick summary

{"Measures short-chain acylcarnitine levels in serum or plasma","Helps diagnose fatty acid oxidation disorders","Used for newborn screening and metabolic disease evaluation","Abnormal results may indicate genetic metabolic conditions","Results help doctors plan appropriate treatment"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
38552-6
Short code
SC-AC
Synonyms
Acylcarnitine SC SerPl-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
2
Ref high
15
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Tandem Mass Spectrometry (MS/MS)
CPT
82017
SNOMED
313336004
Specimen volume
0.5-1 mL serum minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C or below): 2-4 weeks
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

The short-chain acylcarnitine test measures the amount of short-chain acylcarnitine in your blood serum or plasma. Acylcarnitines are substances produced when your body breaks down fatty acids for energy. Short-chain acylcarnitines specifically refer to those with shorter carbon chains. This test helps doctors evaluate how well your body processes fats for energy.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. You may need to fast for several hours before the test, as instructed by your doctor. It's important to follow any pre-test instructions carefully to ensure accurate results.

What do the results mean?

Normal levels of short-chain acylcarnitine indicate that your body is properly metabolizing fatty acids. Abnormal levels, particularly elevated levels, may suggest certain metabolic disorders where the body cannot properly break down fats for energy. Your doctor will interpret your results in combination with your symptoms, medical history, and other test results.

Reference range

Reference ranges for short-chain acylcarnitines vary by compound and laboratory. Typical reference ranges: Acetylcarnitine (C2): 2-15 µmol/L; Propionylcarnitine (C3): 0.5-5 µmol/L. Consult laboratory-specific reference intervals.N/A

Specimen: serum

No special preparation required. Fasting is not mandatory but may be requested for certain clinical indications. Inform patient that this test is commonly used for newborn screening and metabolic disorder evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need this test?
Your doctor may order this test if you have symptoms suggesting a metabolic disorder, such as unexplained muscle weakness, low blood sugar, or developmental delays. It may also be part of routine newborn screening in some regions to detect inherited metabolic conditions early.
Is fasting required before the test?
Fasting may be required for several hours before the test, as eating can affect fatty acid metabolism and potentially alter test results. Follow your doctor's specific instructions about fasting.
What happens if my results are abnormal?
If your results are abnormal, your doctor may recommend additional testing to confirm a diagnosis. This may include repeat testing, genetic testing, or other metabolic tests. If a metabolic disorder is confirmed, treatment may include dietary modifications, medication, and ongoing monitoring.
Is this test safe?
Yes, this test is generally safe. The main risk is minor bleeding, bruising, or infection at the needle insertion site. These complications are rare and usually mild.
  1. 1
  2. 2

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy