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Medical Laboratory Test: A Guide for Patients

Published: August 9, 2026Updated: August 10, 2026

A specialized blood test that measures the level of adenine, a building block of DNA and cellular energy, in your blood serum.

Quick summary

{"Adenine is a natural chemical (nucleotide) found in all cells","This test measures how much adenine is in your blood","It helps doctors check for certain metabolic or kidney problems","The test requires a simple blood draw","Results help diagnose rare genetic or metabolic disorders"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
1719-4
Short code
ADE
Synonyms
Adenine Ser-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
0.2
Ref high
2.5
Fasting
false
Population
adult
Sex
all
Age range
18–100 years
Method
High-Performance Liquid Chromatography (HPLC) with UV detection or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
82175
SNOMED
313295004
Specimen volume
1.0 mL serum minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C or below): 2 weeks. Protect from light.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–72 hours
Order
routine

This is a laboratory test that your healthcare provider may order as part of your routine care or to help evaluate a specific health concern. The test analyzes a sample collected from your body, such as blood, urine, or other tissue, and the results give your care team objective information about how your body is functioning.

The Adenine blood test measures the amount of adenine in your serum (the liquid part of your blood). Adenine is a type of molecule called a nucleotide, which is one of the building blocks of DNA and RNA. It also plays a key role in energy production in your cells as part of a molecule called ATP (adenosine triphosphate).

This test is done to help your doctor check for signs of illness, monitor an ongoing condition, or see how well a treatment is working. In some cases, it is part of a regular checkup to catch potential problems early, before symptoms appear, so that any needed follow-up care can begin as soon as possible.

This test is usually ordered when your doctor suspects a problem with your body's ability to process adenine or other purines (a group of molecules that includes adenine). It may be used to help diagnose certain metabolic disorders, kidney problems, or rare genetic conditions that affect how your body handles these chemicals.

How the test is performed depends on the type of sample your provider needs. Most commonly, a trained staff member draws a small amount of blood from a vein in your arm using a thin needle, a process that usually takes only a few minutes. Other samples, such as urine or a throat swab, can often be collected quickly and comfortably in the office. The sample is then sent to a laboratory, where specialists analyze it and report the findings to your provider.

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood is then sent to a laboratory where the serum (the clear liquid that remains after blood clots) is separated and tested for adenine levels. You do not need to fast or prepare specially for this test in most cases.

Your results will be compared with standard reference ranges to show whether your values fall within the expected limits for a healthy person. Results that are higher or lower than normal do not automatically mean you have a serious condition, since many factors, including medications, diet, and recent activity, can affect the numbers. Your healthcare provider will review the findings with you, explain what they mean in the context of your overall health, and recommend any additional testing or treatment if it is needed.

Normal adenine levels vary by laboratory. Your doctor will interpret your results based on your overall health, symptoms, and other test results. Abnormally high or low levels may indicate a problem with your metabolism or kidney function that needs further evaluation.

Reference range

Reference range varies by laboratory method and population. Typically 0.2-2.5 μmol/L (micromoles per liter). Consult laboratory-specific reference intervals.N/A

Specimen: serum

No specific preparation required. Avoid excessive purine-rich foods 24 hours prior to collection if possible. Inform laboratory of any medications or supplements.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated serum adenine levels may indicate kidney dysfunction, as the kidneys normally help filter and remove adenine from the blood. Certain genetic metabolic disorders, such as adenine phosphoribosyltransferase deficiency, can also affect adenine levels. This test is not commonly ordered and is typically used in specialized settings when a purine metabolism disorder is suspected.

Frequently asked questions

Do I need to fast before this test?
Most patients do not need to fast before an adenine blood test. Follow any specific instructions given by your healthcare provider.
Is this a common test?
No, the adenine serum test is not a routine test. It is a specialized test ordered only when your doctor suspects a specific metabolic or kidney-related condition.
What happens if my adenine level is abnormal?
An abnormal result does not necessarily mean you have a serious problem. Your doctor will consider your symptoms, medical history, and other test results to determine what, if any, follow-up testing or treatment is needed.
Does this test have any risks?
The risks are minimal and are the same as any routine blood draw, including slight bruising, bleeding, or rarely, infection at the needle site.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy