Adenineserplscnc
A blood test that measures the level of adenine, a building block of DNA and RNA, in your blood to evaluate kidney function and purine metabolism.
{"Measures adenine levels in blood serum or plasma","Helps assess kidney function and purine metabolism","Sample collected via routine blood draw","May be ordered to evaluate kidney disease or metabolic disorders","Results are interpreted along with other kidney function tests"}
Key facts at a glance
- LOINC
- 75131-3
- Short code
- Adenine
- Synonyms
- Adenine SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or plain red top tube
- Units
- N/A
- Ref low
- 10
- Ref high
- 50
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
- CPT
- 82175 (Metabolic function, chromatographic assay) or 82679 (Chromatography, mass spectrometry)
- SNOMED
- 314224001
- Specimen volume
- 2-3 mL serum minimum
- Stability
- Serum: Room temperature 24 hours; Refrigerated (2-8°C) 72 hours; Frozen (-20°C or below) stable for several weeks. Protect from light.
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 20
- TAT
- 48–168 hours
- Order
- routine
What is this test?
The adenine blood test measures the amount of adenine in your serum or plasma. Adenine is a nucleobase—an essential building block of DNA and RNA—and is also a component of ATP (adenosine triphosphate), the main energy molecule in your cells. This test helps healthcare providers evaluate how well your kidneys are filtering waste products from your blood and assess disorders related to purine metabolism.
Why is this test performed?
Your doctor may order an adenine test to: evaluate kidney function and detect kidney disease, monitor existing kidney conditions, assess purine metabolism disorders, investigate unexplained fatigue or metabolic problems, or evaluate certain genetic conditions affecting nucleotide processing.
How is the test done?
A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. You do not need to fast or prepare specially for this test, unless your doctor instructs otherwise.
Understanding your results
Abnormal adenine levels may indicate kidney problems, as healthy kidneys help remove adenine from the blood. Elevated levels may suggest reduced kidney function or kidney disease. Your doctor will interpret your results alongside other kidney function tests (such as creatinine and BUN) to get a complete picture of your kidney health.
Reference range
Reference range not firmly established; consult laboratory. Typical reported range: 10-50 nmol/L for adults. Clinical interpretation should be based on specific clinical context and laboratory-specific reference values.N/A
No specific fasting required. Collect specimen using standard venipuncture technique. Avoid hemolysis. Inform laboratory of any medications that may affect purine metabolism.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before this test?
What does a high adenine level mean?
Is this test painful?
How long does it take to get results?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy