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Understanding Your Laboratory Test: Sample Collection and What the Results Mean

Published: August 9, 2026Updated: August 16, 2026

A laboratory test that examines tissue samples under a microscope to identify and characterize adenomas (benign tumors).

Quick summary

{"Adenomas are non-cancerous growths that can develop in various organs","Histology examines tissue structure to determine if growths are benign or malignant","This test helps doctors understand the nature of detected tumors","Results guide treatment decisions and follow-up care","The test is performed on tissue obtained through biopsy or surgery"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
67177-6
Short code
ADH
Synonyms
Adenoma histology PhenX
Category
chemistry
Sample
serum
Container
Tissue container with formalin (10% neutral buffered formalin) or fresh transport container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
phenx
CPT
88305
SNOMED
400550006
Specimen volume
Tissue specimen of adequate size for processing (typically >2mm)
Stability
Formalin-fixed specimens: room temperature, stable for weeks to months. Fresh tissue: process within 1-2 hours
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–72 hours
Order
routine

This laboratory test gives your healthcare provider important information about your health by measuring substances in your body. It can be used to screen for illness, confirm or rule out a diagnosis, monitor an ongoing condition, or check how well a treatment is working. Your provider will explain why this test was ordered for you and what specific findings they are looking for.

The adenoma histology test is a laboratory examination that analyzes tissue samples under a microscope. Adenomas are benign (non-cancerous) tumors that can develop in various organs, including the colon, thyroid, pituitary gland, and adrenal glands. This test helps pathologists determine whether a growth is an adenoma or if it has features that require further investigation.

The way your sample is collected depends on the type of test your provider ordered. Most often, a trained technician draws a small amount of blood from a vein in your arm with a thin needle, a process that usually takes only a few minutes. Some tests instead require a urine sample, a throat or nasal swab, or a saliva sample. You may receive special instructions, such as fasting beforehand, so follow them carefully and tell the staff about any medications you take.

Unlike blood tests that use serum, adenoma histology requires a tissue sample. This tissue is obtained through procedures such as colonoscopy with polyp removal (polypectomy), surgical biopsy, or fine-needle aspiration. The collected tissue is then preserved and sent to a laboratory where a pathologist examines it under a microscope.

Your results are compared with established reference ranges to show whether your values fall within the expected range. A result within the normal range generally suggests no problem in the area being tested, while a value that is too high or too low may point to a condition that needs further evaluation. Keep in mind that factors such as age, medications, and recent meals can affect results, and a single abnormal value does not automatically mean you are ill. Always review your results with your healthcare provider, who can interpret them in the context of your symptoms and medical history and decide whether additional testing or treatment is needed.

The histology results provide important information about the tissue, including: whether the growth is benign (adenoma) or malignant (cancer), the specific type of adenoma, cell characteristics and growth patterns, and whether complete removal was achieved. Your doctor will explain these findings and what they mean for your specific situation.

Reference range

No adenoma present: Negative for adenomatous changes. Adenoma present: Classification by histologic type (tubular, tubulovillous, villous), grade (low-grade, high-grade dysplasia), and focal featuresN/A

Specimen: serum

No specific preparation required. Ensure proper identification and labeling of tissue specimen. Provide relevant clinical history including lesion location, size, and prior procedures

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Adenoma histology testing is crucial for distinguishing benign tumors from malignant cancers. While adenomas themselves are not cancerous, some types may have potential to become cancerous over time (malignant transformation). This test helps identify high-risk adenomas that may require more frequent monitoring or additional treatment. In colorectal cancer screening, detecting and removing adenomatous polyps through colonoscopy is a key prevention strategy.

Frequently asked questions

Is an adenoma the same as cancer?
No, adenomas are benign (non-cancerous) tumors. However, some adenomas may have the potential to develop into cancer over time, which is why they often require removal and follow-up monitoring.
How long does it take to get results?
Histology results typically take 3-7 days, as the tissue processing and microscopic examination require careful analysis by a pathologist.
Do I need to do anything special to prepare?
Preparation depends on how the tissue sample is obtained. For procedures like colonoscopy, you will receive specific instructions about fasting and bowel preparation. Your healthcare provider will give you detailed preparation guidelines.
What happens after adenoma is found?
If an adenoma is confirmed, your doctor will discuss whether complete removal was achieved and recommend an appropriate follow-up schedule. Some patients may need more frequent screenings, while others may only need routine monitoring.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy