Skip to content

Adrenalpathbxreport

Published: August 9, 2026Updated: August 16, 2026

A pathological examination of adrenal gland tissue sample to diagnose tumors, cysts, or other abnormalities.

Quick summary

{"An adrenal gland biopsy involves removing a small tissue sample from the adrenal gland for laboratory analysis","The procedure helps doctors determine whether a mass is benign or cancerous","Results typically indicate the type of cells present and whether they are normal or abnormal","The biopsy is usually guided by imaging techniques like CT or ultrasound","Results help guide further treatment decisions"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
66122-3
Short code
ADRENAL-PATH
Synonyms
Adrenal Path Bx report
Category
chemistry
Sample
serum
Container
10% neutral buffered formalin container for tissue fixation
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Histopathological examination with microscopy, immunohistochemistry, and special stains as needed
CPT
88305 (Level IV Surgical Pathology, Gross and Microscopic), 88307 (Adrenal gland resection), 88312 (Special stains), 88342 (Immunohistochemistry)
SNOMED
399068003 (Adrenal gland tissue), 40055000 (Chronic adrenal insufficiency), 363406005 (Malignant neoplasm of adrenal gland)
Specimen volume
Adrenal tissue biopsy specimen (variable size, typically 1-3 cores or Excisional biopsy)
Stability
Tissue should be placed in formalin immediately after collection. Formalin-fixed tissue is stable at room temperature for processing. Unfixed tissue should be processed within 1-2 hours if frozen sections are required.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is an Adrenal Gland Biopsy?

An adrenal gland biopsy is a diagnostic procedure where a small sample of tissue is removed from the adrenal gland for pathological examination. The adrenal glands are small triangular-shaped glands located on top of each kidney. They produce hormones that regulate metabolism, stress response, and blood pressure. This biopsy helps doctors examine the cellular structure of the adrenal gland to identify abnormalities such as tumors, cysts, or other pathological conditions.

How is the Procedure Performed?

The biopsy is typically performed by inserting a thin needle through the skin and into the adrenal gland. The procedure is usually guided by imaging techniques such as computed tomography (CT) or ultrasound to ensure accurate placement. Local anesthesia is used to minimize discomfort. The tissue sample is then sent to a pathology laboratory where it is examined under a microscope by a pathologist who specializes in diagnosing diseases through tissue analysis.

What Does the Pathology Report Show?

The pathology report provides detailed information about the tissue sample, including: the type of cells present (cortical or medullary), whether the cells appear normal or abnormal, the characteristics of any identified mass (such as tumor type, size, and grade), whether the tissue is benign (non-cancerous) or malignant (cancerous), and whether there are any signs of infection or inflammation. This information is crucial for determining an accurate diagnosis and developing an appropriate treatment plan.

What to Expect After the Procedure

After the biopsy, you may experience some soreness or bruising at the needle insertion site. Most patients can resume normal activities within 24-48 hours. Your doctor will discuss the biopsy results with you during a follow-up appointment, usually within one to two weeks after the procedure. The results will help determine whether additional treatment or monitoring is necessary.

Reference range

Adult: 44-147 U/LN/A

Specimen: serum

Patient should discontinue anticoagulant medications as directed by physician prior to biopsy. Inform the healthcare provider of any bleeding disorders or medications that affect clotting. No fasting required for adrenal biopsy procedure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need an adrenal gland biopsy?
Your doctor may recommend an adrenal biopsy if imaging tests (like CT or MRI) show an abnormal mass or growth on your adrenal gland. The biopsy helps determine whether the mass is benign or cancerous and what type of treatment may be needed.
Is an adrenal biopsy painful?
Local anesthesia is used to numb the area, so you should feel minimal pain during the procedure. You may experience some discomfort or soreness at the biopsy site afterward, which can usually be managed with over-the-counter pain relievers.
How long does it take to get results?
Pathology results typically take 5-10 business days. The tissue sample requires careful processing and examination under a microscope by a pathologist to provide an accurate diagnosis.
Are there any risks associated with this procedure?
While generally safe, potential risks include bleeding, infection, or accidental damage to nearby organs. However, these complications are rare. Your doctor will discuss the specific risks with you before the procedure.
Do I need to fast before the biopsy?
Follow your doctor's specific instructions. You may be asked to fast for several hours before the procedure. Also, inform your doctor about any medications you are taking, as some blood-thinning medications may need to be temporarily stopped.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy