B细胞淋巴细胞计数（绝对值计数）
此项检查测量B细胞的数量。B细胞是一种白细胞，对产生帮助抵抗感染和癌症等疾病的抗体至关重要。
了解您的B细胞计数有助于医生监测免疫功能，并发现影响这些细胞的疾病。
关键信息一览
- LOINC
- 40884-9
- 简码
- CD19CD103
- 别名
- CD19+CD103+ Cells NFr Tiss
- 类别
- 生化
- 样本
- serum
- 采血管
- Sterile 15 mL or 50 mL conical polypropylene tube containing transport medium (RPMI 1640 with heparin or saline); avoid EDTA tubes for tissue specimens intended for flow cytometry when possible.
- 单位
- N/A
- 参考下限
- 1
- 参考上限
- 2
- 是否空腹
- 否
- 适用人群
- 成人
- 性别
- all
- 年龄范围
- 18–65 岁
- 检测方法
- Flow cytometry (immunophenotyping) with multi-color antibody panel targeting CD19 and CD103 surface markers, typically performed on fresh or frozen tissue-derived cell suspensions using fluorescein-conjugated monoclonal antibodies and analyzed on a clinical flow cytometer.
- CPT
- 88184 (Flow cytometry, cell surface, cytoplasmic, or nuclear marker, technical component only; first marker) + 88185 (each additional marker)
- SNOMED
- 1017504007 |Measurement of CD19-positive, CD103-positive cell number in tissue specimen (procedure)|
- 标本量
- Tissue specimen: minimum 0.5 cm³ fresh tissue (approximately 5-10 mm in greatest dimension); cell suspension: minimum 1-2 mL at concentration of 1×10⁶ cells/mL.
- 标本稳定性
- Fresh tissue should be processed within 24 hours when stored at 2-8°C. Cell suspensions may be held up to 48 hours at 2-8°C in appropriate medium. If delays exceed 24 hours, consider cryopreservation in DMSO-containing media. Viability should be assessed prior to analysis (target ≥80%).
- 溶血上限
- 500
- 脂血上限
- 1000
- 黄疸上限
- 500
- 报告时间
- 24–72 小时
- 医嘱频率
- routine
为什么要做这项检查
医生可能会开具B细胞计数检查，以排查免疫系统疾病，例如自身免疫性疾病、感染，或淋巴瘤、白血病等某些癌症。它还可用于评估这些疾病的治疗效果。
检查前的注意事项
无需特殊准备。您可能需要抽血，通常从手臂静脉抽取，与其他血液检查类似。整个过程很快，通常无痛。
检查结果的解读方式
检查结果会与健康成年人的一般参考范围进行比较。计数过高或过低可能提示存在需要进一步医学评估的潜在健康问题。
影响B细胞计数的常见疾病
慢性感染、某些癌症或免疫系统疾病等情况可能导致B细胞增多或减少。例如，B细胞淋巴瘤可能引起计数异常升高，而严重感染或免疫缺陷则可能表现为计数偏低。
Reference range
Reference ranges for CD19+CD103+ cells in tissue are laboratory- and tissue-specific. In normal lymphoid tissues, CD19+CD103+ B-cells are typically present at very low frequency (<1-2% of total B-cells). Results should be interpreted in conjunction with clinical context, tissue type, and concurrent immunophenotypic findings. No universally standardized reference range exists for tissue-based assays.N/A
No specific patient preparation is required for the donor/patient. However, tissue specimen handling is critical: tissue should be delivered to the laboratory in RPMI 1640 or saline immediately upon collection, processed within 24 hours when possible, and maintained at 2-8°C to preserve cell viability and surface antigen integrity. Avoid formalin fixation prior to flow cytometry analysis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
临床意义：B细胞计数在免疫相关疾病的诊断和管理中起关键作用
简称
B细胞计数
常见问题
这项检查的正常值是多少？
我应该多久做一次这项检查？
我可以影响自己的B细胞计数吗？
本信息仅供教育用途，不能替代专业医疗建议、诊断或治疗。
本内容仅供一般信息和教育用途，不能替代专业医疗建议、诊断或治疗。对于任何医疗问题，请务必咨询合格的医疗服务提供者；切勿因阅读本站内容而忽视专业医疗建议或推迟就医。
如果您认为自己可能出现医疗紧急情况，请立即拨打当地急救电话或前往最近的急诊科。
医学审核:WellAlly 编辑团队 最后审核 2026年8月16日. · 阅读我们的编辑政策