脑脊液B细胞计数（CD19+细胞）
该检查用于测量您脑脊液（CSF）中B细胞（一种白细胞）的数量，脑脊液是环绕大脑和脊髓的液体。此项检测有助于评估中枢神经系统的免疫活动情况。
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关键信息一览
- LOINC
- 51353-1
- 简码
- CSFCD19CD58
- 别名
- CD19+CD58+ Cells NFr CSF
- 类别
- 生化
- 样本
- csf
- 采血管
- Sterile CSF collection tubes (polypropylene); specific tube requirements depend on flow cytometry panel used; typically collected sequentially into numbered tubes with tube 3-4 preferred for cell-based analyses to minimize blood contamination
- 单位
- N/A
- 是否空腹
- 否
- 适用人群
- 成人
- 性别
- all
- 年龄范围
- 0–99 岁
- 检测方法
- Flow cytometry (immunophenotyping) using fluorescently-labeled monoclonal antibodies against CD19 and CD58 surface markers, typically with multicolor panel analysis on cerebrospinal fluid cells
- CPT
- 88184 (Flow cytometry, cell surface, cytoplasmic, or nuclear marker, technical component only; first marker) with additional CPT codes for each additional marker (88185 x2 for CD19 and CD58) and 88187-88189 for interpretation as applicable
- SNOMED
- 445532009 (Cerebrospinal fluid specimen) combined with procedure codes for flow cytometry immunophenotyping
- 标本量
- 1-3 mL of CSF minimum; larger volumes (5-10 mL) preferred for adequate cell yield in flow cytometry analysis
- 标本稳定性
- Process specimen within 1-2 hours of collection for optimal cell viability. If delayed, store at 2-8°C and process within 4 hours. Do not freeze. Fixation protocols may be used per laboratory-specific procedures.
- 溶血上限
- 200
- 报告时间
- 4–48 小时
- 医嘱频率
- routine
为何可能需要安排此项检查
如果您出现头痛、颈部僵硬、意识模糊或神经系统问题等症状，提示可能存在影响大脑或脊髓的免疫相关疾病，医生可能会建议您进行此项检查。此外，该检查也用于监测多发性硬化症或自身免疫性疾病等疾病的某些治疗效果。
检查前需要注意什么
该检查无需特殊准备。医生会将一根细针刺入您的腰椎以采集脑脊液。操作过程较快，但可能引起轻微不适。检查后您需侧卧数分钟，以防止脑脊液漏出。
检查结果的含义
检查结果会显示您脑脊液中B细胞（CD19+）的数量。水平升高可能提示脑膜炎、某些癌症（如淋巴瘤）或免疫性疾病。水平较低或正常可能表明您的中枢神经系统没有明显的免疫活动，但仍需进一步检查才能确认。
此项检查可帮助诊断的常见疾病
此项检查有助于诊断或监测慢性炎症性疾病、感染（如病毒性脑膜炎）或与中枢神经系统异常免疫反应相关的罕见神经系统疾病等多种病症。
Reference range
Reference ranges vary by laboratory; typically reported as percentage of total lymphocytes or as absolute count per microliter. CD19+ B-lymphocytes are normally rare or absent in CSF. Clinical interpretation should be performed in conjunction with other CSF parameters.N/A
No special patient preparation required. CSF collection is performed by lumbar puncture by a qualified healthcare provider under sterile conditions. Inform the ordering physician of any bleeding disorders, anticoagulant use, or allergies to local anesthetics prior to the procedure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
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简称
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常见问题
脑脊液中B细胞计数偏高意味着什么？
这项检查需要空腹吗？
多长时间可以拿到检查结果？
本信息仅供教育用途，不能替代专业医疗建议、诊断或治疗。
本内容仅供一般信息和教育用途，不能替代专业医疗建议、诊断或治疗。对于任何医疗问题，请务必咨询合格的医疗服务提供者；切勿因阅读本站内容而忽视专业医疗建议或推迟就医。
如果您认为自己可能出现医疗紧急情况，请立即拨打当地急救电话或前往最近的急诊科。
医学审核:WellAlly 编辑团队 最后审核 2026年8月16日. · 阅读我们的编辑政策