血清IgG2亚类测定(免疫分析法)
此项检查测量血液中特定类型抗体(IgG2)的含量。抗体帮助你的免疫系统抵抗感染和其他疾病。
["IgG2能够保护身体抵抗某些细菌和病毒,低水平可能影响免疫反应。"]
关键信息一览
- LOINC
- 89348-7
- 简码
- CD27IgDIgM
- 别名
- CD27+IgD-IgM+/CD19 cells NFr Bld
- 类别
- 生化
- 样本
- whole-blood
- 采血管
- EDTA (lavender/purple-top) blood collection tube; sodium heparin (green-top) is an acceptable alternative. Tubes must be filled to manufacturer's stated volume.
- 单位
- N/A
- 参考下限
- 0.5
- 参考上限
- 4
- 是否空腹
- 否
- 适用人群
- 成人
- 性别
- all
- 年龄范围
- 0–99 岁
- 检测方法
- Flow cytometry (multi-color immunophenotyping) using CD27, IgD, IgM, and CD19 fluorescently-labeled monoclonal antibodies; reported as percentage of CD19+ B cells or as absolute count via CD45/SSC gating with counting beads.
- CPT
- 86356 (Monoclonal antibody panel for flow cytometry, each additional marker - for individual antibody staining beyond initial panel); commonly billed with 86355 for first marker and 86356 x multiple for additional markers per addended CPT guidance.
- SNOMED
- 416748002 |Flow cytometry (procedure)|; with associated 269929007 |Lymphocyte subset analysis (procedure)|
- 标本量
- 3-5 mL of whole blood for adults; minimum 1-2 mL for pediatric samples.
- 标本稳定性
- Specimen should be processed within 24 hours of collection when stored at room temperature (18-22°C). If processing is delayed beyond 24 hours, store at 2-8°C and process within 48 hours. Do not freeze whole blood. Viability and surface marker integrity decrease significantly after 48 hours.
- 溶血上限
- 100
- 脂血上限
- 500
- 黄疸上限
- 20
- 报告时间
- 24–72 小时
- 医嘱频率
- routine
测试目的
IgG2是五种IgG亚类中的一种,是血液中最常见的抗体。此项检查特别测量IgG2浓度,参与防御某些细菌感染及特定免疫反应。IgG2抗体特别重要,用于保护如链球菌和流感杆菌等被包膜细菌感染。
可能需要此项检查的原因
医生可能会建议做此项检查,如果你患有免疫系统减弱的症状,如反复感染、慢性鼻窦或耳部感染,或者有哮喘、过敏或某些自身免疫性疾病。也可能用于监测HIV/AIDS或其他免疫相关疾病患者的免疫功能。
检查前的准备
此项血检不需特殊准备。可能会在手臂静脉内插入小针头采血,类似于常规血检。如果你在服用血液稀释剂或有出血倾向史,请在检查前告知医生。
检查过程中的体验
从手臂静脉采血,可能会有轻微针刺感,但整个过程通常只需几分钟。血样将送至实验室,通过免疫分析法精确测量IgG2水平。
Reference range
Reference ranges are laboratory- and age-specific. In healthy adults, CD27+IgD-IgM+ (IgM-only) memory B cells typically constitute approximately 0.5% to 4% of total CD19+ B cells, with reported adult median values around 1-2%. Pediatric reference ranges differ and should be established per laboratory. Results must be interpreted in conjunction with the full B-cell subset panel.N/A
No special patient preparation required. Patients on active immunosuppressive or B-cell-depleting therapy (e.g., rituximab, corticosteroids, chemotherapy) may have altered subset distribution; document recent medications and timing of last infusion. Avoid testing within 24-48 hours after recent vaccination when feasible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
简称
IgG2免疫球蛋白水平
常见问题
IgG2水平可能低于正常范围,见于某些免疫缺陷,如选择性IgA缺乏或共变性免疫缺陷。低水平也可能与哮喘、过敏或自身免疫性疾病相关。相反,极高水平较少见,可能与某些免疫性疾病或慢性感染相关。
正常IgG2水平因人而异,没有单一固定范围。结果将与你自身基线或医生提供的参考范围进行比较,可能结合临床背景(如症状和病史)来解释结果。
是的,IgG2水平可能因年龄、感染免疫反应、药物或健康状况变化而波动。如果患有影响免疫系统的疾病,可能需要定期监测。
本信息仅供教育用途,不能替代专业医疗建议、诊断或治疗。
本内容仅供一般信息和教育用途,不能替代专业医疗建议、诊断或治疗。对于任何医疗问题,请务必咨询合格的医疗服务提供者;切勿因阅读本站内容而忽视专业医疗建议或推迟就医。
如果您认为自己可能出现医疗紧急情况,请立即拨打当地急救电话或前往最近的急诊科。
医学审核:WellAlly 编辑团队 最后审核 2026年8月11日. · 阅读我们的编辑政策