外周血CD4细胞计数
这个检查测量的是血液中CD4细胞的数量。CD4细胞是白细胞的一种,能帮助你的免疫系统抵抗感染。
["CD4细胞对于维持免疫功能至关重要。如果CD4细胞数量过低,可能表明免疫力下降。"]
关键信息一览
- LOINC
- 17163-7
- 简码
- CD49a
- 别名
- CD49a Cells NFr Bld
- 类别
- 生化
- 样本
- whole-blood
- 采血管
- EDTA (lavender/purple-top) anticoagulant tube for flow cytometry; alternatively, sodium heparin (green-top) tube may be used. ACD (yellow-top) tubes are also acceptable.
- 单位
- N/A
- 是否空腹
- 否
- 适用人群
- 成人
- 性别
- all
- 年龄范围
- 18–65 岁
- 检测方法
- Flow cytometry using monoclonal antibodies targeting CD49a (integrin alpha-1, ITGA1) surface marker, typically performed on fresh whole blood with fluorescein (FITC) or phycoerythrin (PE) conjugated anti-CD49a antibodies; results expressed as percentage of CD49a-positive lymphocytes or absolute cell count per unit volume
- CPT
- 86356 (for flow cytometry, cell surface marker, technical component only; additional CPT codes may apply based on panel composition)
- SNOMED
- 116849008 (Cell surface marker measurement)
- 标本量
- 3-5 mL of whole blood in EDTA tube; minimum 1 mL required for pediatric samples. For absolute counts, a CBC with differential should be performed concurrently.
- 标本稳定性
- Specimen should be processed within 24 hours of collection when stored at room temperature (18-25°C). If delayed, samples may be stored at 2-8°C for up to 48 hours; however, viability and marker expression may decline. Do not freeze whole blood samples.
- 溶血上限
- 100
- 脂血上限
- 500
- 黄疸上限
- 20
- 报告时间
- 24–72 小时
- 医嘱频率
- routine
为什么要进行这个检查很重要
CD4细胞是免疫系统的重要组成部分,能帮助身体抵抗病毒、细菌和真菌等感染。低CD4细胞数可能表明免疫力减弱,特别是在HIV或某些自身免疫性疾病中常见。
检查的原理是什么
从静脉中抽取血样,通常从手臂抽取。样本会通过专门的血液检测分析,识别并计算CD4细胞数量。
检查前后需要注意什么
不需要特殊准备,但检查前1小时避免剧烈运动或进食大餐。抽血后可能在抽血部位出现轻微青紫或不适,通常很快会消失。
常见的检查原因是什么
医生可能会根据需要进行此检查,以监测免疫健康、诊断HIV、评估治疗进展或检查免疫缺陷。
Reference range
Reference ranges for CD49a+ cells in peripheral blood are not well established and may vary significantly by laboratory. Generally, CD49a expression on peripheral blood lymphocytes is low under normal conditions; reported ranges typically fall between 0.1% and 2.5% of total lymphocytes. Results should always be interpreted in conjunction with clinical context and laboratory-specific reference intervals.N/A
No special fasting or dietary restrictions are required. Patients should inform their healthcare provider of any recent infections, vaccinations, immunosuppressive therapies, or medications that may alter immune cell populations. Avoid scheduling the test during acute illness when possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
临床意义是什么
简称
CD4 T细胞计数
常见问题
CD4细胞数量过低(具体阈值因人而异)可能表明免疫抑制,需要更密切监测或调整治疗。CD4细胞数量过高可能表明免疫功能正常或过度活跃,但需要进一步评估,若症状持续存在。
你的结果会由医生详细解释,结合你的健康状况。他们可能建议进一步检查或调整治疗方案。
可以要求医生将CD4细胞计数与其他实验室结果(如HIV病毒载量)一并分析。
本信息仅供教育用途,不能替代专业医疗建议、诊断或治疗。
本内容仅供一般信息和教育用途,不能替代专业医疗建议、诊断或治疗。对于任何医疗问题,请务必咨询合格的医疗服务提供者;切勿因阅读本站内容而忽视专业医疗建议或推迟就医。
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医学审核:WellAlly 编辑团队 最后审核 2026年8月15日. · 阅读我们的编辑政策