Omega-3多不饱和脂肪酸（鱼油）补充与炎症预防

发布:2026年7月22日更新:2026年7月22日

Siscovick DS, Barringer TA, Fretts AM, Wu JH, Lichtenstein AH, Costello RB等

Circulation · 2017; 135(15):e867-e884

本综述评估Omega-3 polyunsaturated fatty acid (fish oil) supplements containing eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA), typically 1 gram or more per day与Occurrence of clinical cardiovascular disease events such as heart attack, stroke, heart failure hospitalization, or cardiovascular death的关系。证据等级：Ia。

摘要速览

循证研究：Omega-3多不饱和脂肪酸与炎症

医学审核:WellAlly 编辑团队最后审核 2026年7月22日编辑政策

关键信息一览

DOI: 10.1161/cir.0000000000000482
PMID: 28289069
PMC: PMC6903779
期刊: Circulation
年份: 2017
卷: 135
期: 15
页码: e867-e884
研究类型: 指南
证据等级: Ia
干预措施: Omega-3 polyunsaturated fatty acid (fish oil) supplements containing eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA), typically 1 gram or more per day
主要终点: Occurrence of clinical cardiovascular disease events such as heart attack, stroke, heart failure hospitalization, or cardiovascular death
随访时长: Varied across trials (typically 1-5 years)
资金来源: 未知
开放获取: 否

研究概述

本研究探讨了Omega-3 polyunsaturated fatty acid (fish oil) supplements containing eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA), typically 1 gram or more per day对Occurrence of clinical cardiovascular disease events such as heart attack, stroke, heart failure hospitalization, or cardiovascular death的影响。

关键发现

研究结果为Occurrence of clinical cardiovascular disease events such as heart attack, stroke, heart failure hospitalization, or cardiovascular death提供了重要证据。

临床结论

详见原始文献。证据等级：Ia。

Abstract

"本临床指南综述了Omega-3 polyunsaturated fatty acid (fish oil) supplements containing eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA), typically 1 gram or more per day与Occurrence of clinical cardiovascular disease events such as heart attack, stroke, heart failure hospitalization, or cardiovascular death的研究证据。

Funding & conflicts of interest

资金来源: unknown

COI: None reported for the advisory writing group beyond standard AHA disclosures