Drug comparisons
Ergotamine vs Lasmiditan
Ergotamine constricts blood vessels but has black box warning for heart risks, while Lasmiditan is 5-HT1F agonist without vasoconstriction.
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Clinical context
Patients with acute migraine and cardiovascular risk factors compare Ergotamine vs Lasmiditan for treatment.
Bottom line
Lasmiditan is generally safer than Ergotamine due to its non-vasoconstrictive mechanism and lack of black box warning.
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