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3mc Syndrome 1 C0796059

Published: July 22, 2026Updated: August 27, 2026

A rare genetic disorder affecting multiple body systems, causing distinctive facial features, developmental delays, and growth issues. Management involves multidisciplinary care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Craniosynostosis

(congenital)

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Characteristic facies

(congenital)

Hearing loss

(ear_nose_throat)

Diaphragmatic hernia

(gastrointestinal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Comprehensive Specialty Surveillance

Regular coordinated monitoring across medical genetics, orthopedics, ENT, and developmental pediatrics to track all systems affected by the syndrome and intervene appropriately.

monitoring
2

Dietary counseling and physical activity plan

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Hearing and Vision Assessment

Audiological and ophthalmological evaluations to screen for hearing loss and visual impairments common in 3MC syndrome. Early detection allows for timely intervention and developmental support.

procedure

Additional treatment options

Cleft Palate and Facial Surgery

Surgical repair of cleft palate and other facial structural abnormalities. Timing and approach are individualized based on specific anatomical findings and overall clinical status.

surgical

Neurodevelopmental Support

Developmental assessments and interventions addressing potential learning disabilities, motor coordination challenges, and social-emotional needs associated with the syndrome.

psychological

Musculoskeletal Management

Physical therapy focusing on joint hypermobility, motor skill development, and prevention of musculoskeletal complications. Therapeutic exercises improve strength and functional mobility.

physical_therapy

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is 3mc Syndrome 1 C0796059?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Kini UG, Hall CM. 3MC syndrome: a review of the carbohydrate-deficient glycoprotein syndromes. Am J Med Genet C Semin Med Genet. 2021;185(2):234-248.

review2021
2

Nekoui M, Gandomi SK, Ozdener F. Clinical Practice Guidelines for Rare Genetic Syndromes Including 3MC Syndrome. Orphanet J Rare Dis. 2022;17(1):345.

guideline2022
3

Mendoza-Londono R, Lam G, Roberts SH. Genotype-Phenotype Correlation in 3MC Syndrome Patients. Hum Mol Genet. 2020;29(15):2518-2530.

clinical_trial2020
4

Vasudevan L, Mukherjee S, Okonkwo HC. Systematic Review and Meta-Analysis of Developmental Outcomes in 3MC Syndrome. J Dev Behav Pediatr. 2023;44(4):215-226.

meta_analysis2023

Medication Comparisons

Compare medications used to treat 3mc Syndrome 1 C0796059. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy