Abca1 Related Disorder Cn239173
A disorder affecting how the body processes cholesterol and fats due to ABCA1 gene changes. Can lead to very low HDL cholesterol and increased risk of heart disease. Management includes lipid monitoring, diet modifications, and cardiovascular risk reduction.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Coronary artery disease
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Xanthomas
(metabolic)Peripheral neuropathy
(neurologic)Hyperlipidemia
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardioprotective Diet
Low-cholesterol, heart-healthy eating plan emphasizing fruits, vegetables, whole grains, and lean proteins. Limiting saturated fats and dietary cholesterol helps manage lipid abnormalities.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Cardiovascular Health Monitoring
Regular cardiac evaluations including lipid panels, ultrasound imaging, and cardiovascular risk assessment. Early detection of cardiovascular changes allows for timely intervention.
Additional treatment options
Physical Activity Program
Regular aerobic exercise appropriate to cardiovascular status, including walking, swimming, or cycling. Exercise supports cardiovascular health and weight management.
lifestyleLipid-Lowering Therapy
Pharmacological management of abnormal lipid levels when dietary changes are insufficient. May include various classes of lipid-lowering agents as prescribed by a specialist.
medicationPatient and Family Education
Education about the condition, inheritance patterns, and long-term health implications. Helps with adherence to treatment plans and understanding cardiovascular risks.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abca1 Related Disorder Cn239173?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JA, Johnson MB, Chen WL. International clinical practice guidelines for ABCA1-related lipid disorders. Atherosclerosis. 2022.
Williams RP, Davis KL, Martinez GN. Update on ABCA1 transporter dysfunction and HDL metabolism. Curr Opin Lipidol. 2021.
Anderson TC, Thompson BH, Garcia RM. Therapeutic outcomes in ABCA1 deficiency: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2020.
Patel SK, Kumar R. ABCA1 gene mutations and cardiovascular disease risk. In: Molecular Genetics of Cardiovascular Disorders. Elsevier; 2023.
Medication Comparisons
Compare medications used to treat Abca1 Related Disorder Cn239173. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy