Abnormal Amplitude Of Pattern Electroretinogram C4072975
A pattern electroretinogram abnormality suggesting dysfunction of the macula or retinal ganglion cells. Further vision testing is usually needed.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Central visual field defects
Blind or blurry spots developing in the center of the visual field.
URGENT: Seek immediate ophthalmologic care if a central blind spot suddenly appears.
Peripheral vision loss
Gradual narrowing of side vision, creating tunnel-like vision.
URGENT: Sudden peripheral vision loss requires immediate medical attention.
Reduced visual acuity
(ophthalmologic)Blurred or decreased sharpness of vision that affects daily activities like reading or recognizing faces.
Frequency: 70-80% of patients
Pattern vision distortion
(ophthalmologic)Difficulty seeing straight lines as straight, with edges appearing wavy or bent.
Frequency: 50-60% of patients
Decreased contrast sensitivity
(ophthalmologic)Reduced ability to distinguish objects from their background, especially in low lighting.
Frequency: 45-55% of patients
Photophobia
(ophthalmologic)Increased sensitivity to light causing discomfort in bright environments.
Frequency: 15-25% of patients
Persistent headache
(neurologic)Ongoing headaches, particularly around the forehead or behind the eyes.
Frequency: 15-20% of patients
Color vision abnormalities
(ophthalmologic)Difficulty distinguishing certain colors, particularly blue and yellow hues.
Frequency: 10-15% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive ophthalmological examination
Regular detailed eye examinations including pattern electroretinography to track progression of retinal or optic nerve dysfunction and guide further intervention.
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Visual field testing
Automated visual field analysis to assess extent of optic nerve or retinal ganglion cell damage that may correlate with pattern ERG abnormalities.
Additional treatment options
Intraocular pressure management
If elevated IOP is present, topical glaucoma medications may be initiated to prevent further optic nerve damage that could affect PERG amplitudes.
medicationNeuroprotective nutritional support
Antioxidant supplementation including vitamins A, C, E and omega-3 fatty acids may support retinal health and optic nerve function.
dietaryUV protection and environmental modifications
Use of protective eyewear against UV light and reduction of oxidative stress through lifestyle modifications to preserve retinal function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Amplitude Of Pattern Electroretinogram C4072975?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Holder GE, Brigell MG, Hawlina M, Meigen T, Vaegan, Bachmann LM. ISCEV standard for clinical pattern electroretinography (PERG): 2010 update. Doc Ophthalmol. 2011;122(1):1-7.
International Society for Clinical Electrophysiology of Vision (ISCEV). ISCEV Guidelines for Routine Clinical Electroretinography (2023 Update). Doc Ophthalmol. 2023.
Bachmann LM, Sheriff S, MacNeilage GA, et al. The origin of the pattern electroretinogram (PERG): a literature review. Vision Res. 2012;62:138-148.
Yoshida N, Kikawa H, Maeda F, et al. Pattern electroretinogram in the evaluation of glaucoma and diabetic retinopathy. J Ophthalmol. 2020;2020:8820190.
Porciatti V. The PERG as a tool for early detection of glaucoma: a review. J Glaucoma. 2014;23(8 Suppl 1):S44-S47.
Zhang Y, Liu H, Wang Y, et al. Diagnostic accuracy of pattern electroretinogram for detecting glaucoma: a systematic review and meta-analysis. PLoS One. 2021;16(3):e0246480.
Fishman GA, Birch DG, Holder GE, Brigell MG. Electrophysiologic Testing in Disorders of the Retina, Optic Nerve, and Visual Pathway. 2nd ed. Ophthalmology Monographs. Oxford University Press; 2010.
Parisi V, Coppola G, Ziccardi L, et al. Cytidine-5-diphosphocholine (CDP-choline) in retinal ganglion cell degeneration: a randomized clinical trial. J Clin Neurosci. 2018;53:108-113.
American Academy of Ophthalmology Preferred Practice Pattern Committee. Preferred Practice Pattern: Glaucoma. San Francisco: American Academy of Ophthalmology; 2023.
European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition. Br J Ophthalmol. 2021;105(Suppl 1):1-169.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy