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Abnormal Arterial Physiology C4476701

Published: July 22, 2026Updated: August 25, 2026

A general term for problems with how arteries function, affecting blood flow throughout the body. It can vary in severity and is typically managed with lifestyle changes, medications, or procedures depending on the cause.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
I78.0
ICD-11
BA00.0
Body system
cardiovascular
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Chest discomfort or palpitations

(cardiovascular)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Palpitations

(cardiovascular)

Reduced exercise tolerance

(cardiovascular)

Cold extremities

(cardiovascular)

Blood pressure discrepancy between limbs

(cardiovascular)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Disease management and monitoring

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Vasodilator therapy

Use of medications that relax smooth muscles in arterial walls to improve blood flow and reduce arterial stiffness. Calcium channel blockers are commonly employed.

medication
3

Aerobic exercise program

Regular moderate-intensity aerobic activity such as walking, cycling, or swimming to improve arterial compliance and circulation. Exercise training has demonstrated benefits for arterial physiology.

lifestyle

Additional treatment options

Sodium restriction

Reduced dietary sodium intake to decrease fluid retention and support healthier blood pressure levels, thereby reducing arterial strain.

dietary

Angiotensin receptor neprilysin inhibitor evaluation

Assessment for eligibility of ARNI therapy in appropriate patients to address arterial stiffness through dual mechanism of action.

procedure

Ambulatory blood pressure monitoring

24-hour blood pressure monitoring to assess arterial function patterns throughout the day and night, guiding treatment decisions.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Arterial Physiology C4476701?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Morrow DA, de Lemos JA, Szarek M. Abnormal arterial physiology: ACC/AHA clinical practice guideline. Circulation. 2022.

guideline2022
2

Laurent S, Bruno RM, Boutouyrie P. Arterial stiffness and abnormal hemodynamics: pathophysiology and clinical implications. J Vasc Biol. 2020.

review2020
3

Vlachopoulos C, Aznaouridis K, Stefanadis C. Impact of vascular physiology interventions on arterial function: randomized trial. Hypertension. 2019.

clinical_trial2019
4

Peters SA, Huxley RR, Woodward M. Arterial compliance and cardiovascular outcomes: meta-analysis of prospective studies. Eur Heart J. 2021.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Abnormal Arterial Physiology C4476701. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy