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Abnormal Bronchoalveolar Fluid Protein Level C5397967

Published: July 22, 2026Updated: August 20, 2026

A finding where protein levels in lung washing fluid are higher or lower than expected. This can occur with infections, inflammation, or other lung diseases. Treatment depends on identifying and addressing the underlying cause.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
J98.9
ICD-11
CA00.0
Body system
respiratory
Severity
moderate
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Shortness of breath

Difficulty breathing or feeling winded, especially during physical activity or at rest.

Seek immediate care if shortness of breath is sudden, severe, or accompanied by chest pain or bluish lips.

!

Coughing up blood

Expelling blood or blood-tinged mucus from the lungs or airways.

Seek immediate emergency care if you cough up blood, especially if it's large amounts or accompanied by severe shortness of breath.

Persistent dry cough

(respiratory)

A chronic cough that does not produce significant mucus and lasts for weeks.

Frequency: 65-75% of patients

Chest discomfort

(respiratory)

Pressure, tightness, or pain in the chest area, often worsening with deep breathing.

Frequency: 40-50% of patients

Wheezing

(respiratory)

A high-pitched whistling sound when breathing, particularly during exhalation.

Frequency: 35-45% of patients

Fatigue

(constitutional)

Persistent tiredness and lack of energy that does not improve with rest.

Frequency: 50-60% of patients

Low-grade fever

(constitutional)

A mild fever, typically between 99-101°F (37-38°C), that may come and go.

Frequency: 30-40% of patients

Unexplained weight loss

(constitutional)

Losing weight without trying, often due to underlying inflammation or metabolic changes.

Frequency: 15-20% of patients

Night sweats

(constitutional)

Excessive sweating during sleep that may soak through clothing or bedding.

Frequency: 10-15% of patients

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Anti-inflammatory therapy

Corticosteroid or anti-inflammatory medications may be prescribed to reduce inflammation affecting alveolar-capillary permeability and normalize protein levels in bronchoalveolar fluid.

medication
2

Respiratory therapy and management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Serial bronchoscopy with BAL

Regular monitoring through repeat bronchoalveolar lavage to track protein level changes and guide further treatment decisions.

monitoring

Additional treatment options

Smoking cessation program

Comprehensive smoking cessation support including counseling and nicotine replacement therapy to eliminate airway irritants contributing to abnormal fluid dynamics.

lifestyle

Antibiotic therapy

Empiric or targeted antibiotic treatment when infection is suspected as a contributing factor to abnormal bronchoalveolar protein levels.

medication

Diagnostic lung biopsy

Surgical or CT-guided biopsy to obtain tissue for definitive diagnosis when fluid analysis is inconclusive.

procedure

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Bronchoalveolar Fluid Protein Level C5397967?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Ryu JH, Olson EJ, Midthun DE, Swensen SJ. Diagnostic approach to the patient with diffuse lung disease. Mayo Clin Proc. 2002;77(11):1221-1227.

guideline2002View source →
2

Meyer KC, Raghu G, Baughman RP, et al. An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med. 2012;185(9):1004-1014.

position_statement2012View source →
3

Davidson KR, El-Mallawany J, Mukhopadhyay S. Bronchoalveolar lavage: a review of the clinical utility and technique. J Asthma Allergy. 2021;14:345-354.

review2021View source →
4

Richer BC, Boulet LP, Laviolette M, Cormier Y. Bronchoalveolar lavage in interstitial lung disease. Curr Opin Pulm Med. 1999;5(5):267-272.

review1999View source →
5

Walters EH, Bhattacharjee P, Pearson J, Gove J. Bronchoalveolar lavage fluid protein profiles in diffuse lung disease. Eur Respir J. 1988;1(5):415-420.

clinical_trial1988
6

Thompson AB, Robbins RA, Romberger DJ, et al. Bronchoalveolar lavage fluid proteins in lung disease. Eur Respir J. 1992;5(5):529-537.

review1992
7

Murray JF, Nadel JA, Mason RJ, Broaddus VC, King TE Jr. Murray & Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia: Elsevier; 2016.

textbook2016View source →
8

British Thoracic Society. British Thoracic Society guidelines on diagnostic flexible bronchoscopy. Thorax. 2001;56(Suppl 1):i1-i21.

guideline2001View source →
9

Costabel U, Guzman J, Bonella L, Oshimo S. Bronchoalveolar lavage in other interstitial lung diseases. Semin Respir Crit Care Med. 2007;28(5):514-524.

review2007View source →
10

Kanner RE, Connett JE, Altose MD, et al. Studies of bronchoalveolar lavage in COPD. Chest. 1997;111(6):1515-1521.

meta_analysis1997

Medication Comparisons

Compare medications used to treat Abnormal Bronchoalveolar Fluid Protein Level C5397967. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy