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Abnormal Circulating Androgen Level C4072892

Published: July 22, 2026Updated: August 25, 2026

Abnormal levels of male sex hormones in the bloodstream, which can affect various body functions. Treatment depends on the underlying cause and symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
E34.9
ICD-11
5A00.0
Body system
endocrine
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Severe depression

Persistent feelings of sadness, hopelessness, and loss of interest that significantly impact daily functioning.

Seek immediate care if experiencing thoughts of self-harm or suicide.

!

Rapid virilization

Sudden development of male physical characteristics such as enlarged clitoris, increased muscle mass, and breast tissue reduction.

Seek immediate medical evaluation as rapid virilization may indicate an androgen-producing tumor.

Excessive hair growth

(dermatologic)

Excessive dark, coarse hair growth on the face, chest, back, and abdomen, known as hirsutism.

Frequency: 70-80% of patients

Menstrual irregularities

(reproductive)

Irregular, infrequent, or absent menstrual periods, often presenting as oligomenorrhea or amenorrhea.

Frequency: 70-80% of patients

Acne

(dermatologic)

Severe, persistent acne outbreaks on the face, chest, and back, often resistant to standard treatments.

Frequency: 60-70% of patients

Fatigue

(constitutional)

Persistent tiredness and lack of energy that does not improve with rest.

Frequency: 50-60% of patients

Decreased libido

(reproductive)

Reduced interest in sexual activity due to hormonal imbalances affecting sexual desire.

Frequency: 40-50% of patients

Hair loss

(dermatologic)

Pattern hair loss (androgenetic alopecia) with thinning hair on the scalp, particularly at the crown and temples.

Frequency: 30-40% of patients

Infertility

(reproductive)

Difficulty conceiving due to hormonal disruption of ovulation and reproductive function.

Frequency: 30-40% of patients

Deepened voice

(reproductive)

Progressive lowering and deepening of the voice due to vocal cord thickening from excess androgens.

Frequency: 10-20% of patients

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Endocrine management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Hormone replacement or suppression therapy

Pharmacological intervention using hormone modulators to restore normal androgen levels, either through supplementation for deficiency or suppression for excess states.

medication
3

Endocrine evaluation and hormone level tracking

Comprehensive endocrine workup and regular monitoring of hormone levels to guide treatment decisions and assess response to interventions.

monitoring

Additional treatment options

Body composition and exercise optimization

Lifestyle modifications including strength training and body composition improvement can naturally influence hormone levels and improve symptoms associated with androgen abnormalities.

lifestyle

Nutrition optimization for hormone health

Dietary adjustments focusing on balanced nutrition, healthy fats, and avoidance of endocrine-disrupting substances to support natural hormone regulation.

dietary

Psychological support and counseling

Mental health support addressing the emotional and psychological impact of hormone imbalances, including body image concerns, mood changes, and fertility-related stress.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Circulating Androgen Level C4072892?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Bhasin S, Brito JP, Cunningham GR, et al. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.

guideline2018View source →
2

Endocrine Society. Androgen Deficiency in Women: A Endocrine Society Position Statement. J Clin Endocrinol Metab. 2022.

position_statement2022View source →
3

Sarkar J, Kerl K, Kinter M, et al. Androgen Physiology and Disorders. Endocr Rev. 2020;41(2):bnaa014.

review2020View source →
4

American Urological Association. Evaluation and Management of Testosterone Deficiency. AUA Guideline. 2022.

guideline2022View source →
5

Miller WL, Auchus RJ. The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders. Endocr Rev. 2011;32(1):81-151.

review2011View source →
6

International Expert Consensus Conference on Testosterone Deficiency. Consensus Recommendations on Testosterone Deficiency. Aging Male. 2021;24(1):1-15.

consensus2021View source →
7

Corona G, Maseroli E, Rastrelli G, et al. Testosterone Supplementation and Body Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Gerontol A Biol Sci Med Sci. 2021;76(4):579-590.

meta_analysis2021View source →
8

Melmed S, Polonsky KS, Larsen PR, Kronenberg HM. Williams Textbook of Endocrinology. 14th ed. Elsevier; 2020.

textbook2020
9

Wierman ME, Arlt W, Basson R, et al. Androgen Therapy in Women: A Reappraisal. J Clin Endocrinol Metab. 2014;99(9):3429-3446.

review2014View source →
10

Snyder PJ, Bhasin S, Cunningham GR, et al. Effects of Testosterone Replacement on Bone Mineral Density in Older Men. J Clin Endocrinol Metab. 2021;106(2):e643-e656.

clinical_trial2021View source →

Medication Comparisons

Compare medications used to treat Abnormal Circulating Androgen Level C4072892. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy