Abnormal Circulating Igd Concentration C5139424
A condition where IgD antibody levels are abnormal. It can occur in anyone and is often found during blood tests. Treatment focuses on addressing the underlying cause.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent respiratory infections
(immunologic)Chronic rhinosinusitis
(immunologic)Eczematous rash
(immunologic)Unexplained fatigue
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Immunologic function assessment
Regular evaluation of overall immune function and infection history to determine if IgD abnormalities require active intervention or supportive care only.
Infection prophylaxis when indicated
Antibiotic or antimicrobial prophylaxis for patients with IgD abnormalities who experience recurrent bacterial infections requiring preventive intervention.
Additional treatment options
Immune-supporting daily routine
Establishment of consistent sleep patterns, regular exercise, and stress management to optimize natural immune function and resistance.
lifestyleImmune-nutrient adequate nutrition
Dietary intake supporting immune health including adequate protein, zinc, selenium, and vitamins A, C, D, and E through whole food sources.
dietaryChronic immune condition counseling
Psychological support addressing anxiety related to immunodeficiency concerns and developing coping strategies for managing recurrent infections.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Igd Concentration C5139424?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bonilla FA, Khan DA, Ballas ZK, et al. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol Pract. 2017.
Cunningham-Rundles C. Autoimmune manifestations in primary immunodeficiency disorders. Immunol Allergy Clin North Am. 2019.
Jolles S, Orange JS, Hagan JB, et al. Immunoglobulin replacement therapy for primary immunodeficiency: a randomized controlled trial. J Clin Immunol. 2018.
Perez EE, Orange JS, Bonilla F, et al. Update on the use of immunoglobulin in human disease: a systematic review. Allergy. 2020.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy