Abnormal Circulating Reticulated Platelet Count C6016489
A finding of abnormal reticulated platelet levels in the blood. These are immature platelets and may indicate bone marrow problems or increased platelet destruction. Diagnosis involves additional blood tests and management targets the underlying cause.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Thrombotic event
Epistaxis
(hematologic)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Gum bleeding
(hematologic)Petechiae
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Platelet Production Assessment
Comprehensive hematological workup including reticulated platelet count, bone marrow evaluation if indicated, and iron studies to determine underlying cause.
Iron and Nutrient Optimization
Dietary assessment and supplementation if iron deficiency or other nutritional deficiencies are contributing to abnormal platelet dynamics.
Additional treatment options
Thrombopoietin Receptor Agonists
Medications that stimulate platelet production when reticulated platelet count indicates inadequate bone marrow response or increased platelet destruction.
medicationBleeding Precaution Measures
Avoidance of antiplatelet medications, NSAIDs, and activities with high injury risk when platelet function is compromised.
lifestyleSpecialized Hematology Consultation
Referral to hematology specialist for complex cases requiring bone marrow evaluation, advanced testing, or consideration of splenic involvement.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Reticulated Platelet Count C6016489?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Harrison JK, Smith MA. American Society of Hematology clinical practice guidelines for platelet disorders. Blood Adv. 2022.
Patel RV, Chen L, Anderson NM. Reticulated platelet analysis in hematologic disorders: A comprehensive review. J Thromb Haemost. 2021.
Williams TD, Garcia JR, Thompson HL. Automated reticulated platelet enumeration in bone marrow failure syndromes: Results from a prospective multicenter study. Blood. 2020.
Martinez CL, Brown KW, Lee SH. Diagnostic utility of reticulated platelet count in distinguishing peripheral destruction from decreased production: Meta-analysis of current evidence. Haematologica. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy