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Abnormal Circulating Vitamin D Concentration C4022035

Published: July 22, 2026Updated: August 20, 2026

Vitamin D abnormalities affect bone health and immune function. Risk factors include limited sun exposure and certain medical conditions. Treatment involves supplementation and sun exposure.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E88.9
ICD-11
5A00.0
Body system
metabolic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Seizures

Sudden, uncontrolled electrical disturbances in the brain that can cause convulsions and loss of consciousness

This is a medical emergency. Seek immediate emergency care if a seizure occurs

!

Cardiac arrhythmias

Irregular heartbeats that may present as palpitations, dizziness, or fainting episodes

Seek immediate medical attention if experiencing chest pain, severe dizziness, or fainting

Fatigue

(constitutional)

Persistent tiredness and lack of energy that interferes with daily activities and does not improve with rest

Frequency: 70-80% of patients

Bone pain

(musculoskeletal)

Dull, aching pain in the bones, particularly affecting the lower back, hips, and legs

Frequency: 50-60% of patients

Muscle weakness

(musculoskeletal)

Reduced muscle strength, particularly in the proximal muscles of the thighs and shoulders

Frequency: 40-50% of patients

Muscle aches

(musculoskeletal)

Generalized muscle pain and tenderness, often described as diffuse or nonspecific

Frequency: 30-40% of patients

Depression

(neurologic)

Persistent low mood, loss of interest in activities, and feelings of hopelessness

Frequency: 15-20% of patients

Frequent infections

(immune)

Increased susceptibility to infections due to impaired immune function

Frequency: 10-15% of patients

Impaired wound healing

(dermatologic)

Slow or incomplete healing of cuts, wounds, and surgical incisions

Frequency: 10-15% of patients

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Healthy lifestyle changes and stress management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Vitamin D supplementation

Oral vitamin D supplementation to correct deficiency or normalize elevated concentrations. Treatment approach involves individualized dosing based on baseline levels and ongoing monitoring to achieve target range.

medication
3

Sun exposure and outdoor activity

Increased deliberate sun exposure to promote endogenous vitamin D synthesis through UVB radiation. Treatment approach balances adequate exposure for production with skin cancer prevention guidelines.

lifestyle

Additional treatment options

Vitamin D-rich dietary modification

Incorporation of vitamin D-rich foods such as fatty fish, fortified dairy products, and egg yolks into the diet. Treatment approach provides supportive nutrition alongside other interventions.

dietary

Serum vitamin D level tracking

Regular blood testing to monitor 25-hydroxyvitamin D levels and adjust treatment accordingly. Treatment approach ensures therapeutic targets are met while avoiding toxicity.

monitoring

Calcium co-supplementation

Concurrent calcium supplementation when vitamin D deficiency affects bone health and calcium absorption. Treatment approach supports skeletal integrity during vitamin D correction.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Circulating Vitamin D Concentration C4022035?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911-1930.

guideline2011View source →
2

Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academies Press; 2011.

guideline2011View source →
3

Pilz S, Marz W, Cashman KD, et al. Rationale and plan for vitamin D food fortification: a review and guidance paper. Front Endocrinol. 2018;9:373.

review2018View source →
4

Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort studies and randomised trials. BMJ. 2014;348:g1903.

meta_analysis2014View source →
5

American Geriatrics Society Workgroup on Vitamin D Supplementation for Older Adults. Recommendations abstracted from the American Geriatrics Society consensus conference on vitamin D supplementation for older adults. J Am Geriatr Soc. 2014;62(2):147-152.

position_statement2014View source →
6

Cashman KD, Dowling KG, Škrábáková Z, et al. Vitamin D deficiency in Europe: pandemic? Am J Clin Nutr. 2016;103(4):1033-1044.

review2016View source →
7

Perras C, Tsaknis S. Vitamin D and Calcium Supplementation: Guidelines. Canadian Task Force on Preventive Health Care. 2015.

guideline2015View source →
8

Zhang Y, Fang F, Tang J, et al. Association between vitamin D supplementation and mortality: systematic review and meta-analysis. BMJ. 2019;366:l4673.

meta_analysis2019View source →
9

Wacker M, Holick MF. Vitamin D—effects on skeletal and extraskeletal health and the need for supplementation. Nutrients. 2013;5(1):111-148.

review2013View source →

Medication Comparisons

Compare medications used to treat Abnormal Circulating Vitamin D Concentration C4022035. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy