Abnormal Leukocyte Count C0580531
A finding of too many or too few white blood cells in the blood. This can occur with infections, immune disorders, or blood diseases. Treatment focuses on identifying and addressing the underlying cause.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Frequent infections
(hematologic)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Fever
(hematologic)Fatigue
(hematologic)Oral ulcers
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Colony-Stimulating Factors
Administration of granulocyte or granulocyte-macrophage colony-stimulating factors to stimulate bone marrow production of white blood cells. This addresses neutropenia by promoting leukocyte proliferation and release.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Complete Blood Count Monitoring
Regular CBC testing to track leukocyte trends and identify patterns or triggers for abnormal counts. Enables early intervention before infections develop.
Additional treatment options
Nutritional Support for Hematopoiesis
Dietary optimization with adequate protein, vitamins B12, folate, and iron to support bone marrow function. Nutritional deficiencies can contribute to abnormal leukocyte production.
dietaryInfection Prevention Strategies
Education on hygiene practices, food safety, and early infection recognition. Reduces morbidity from opportunistic infections when leukocyte function is impaired.
lifestyleTreatment of Underlying Cause
Addressing primary conditions causing leukocyte abnormalities such as infections, autoimmune disorders, or medication effects. Correcting the root cause often normalizes cell counts.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Leukocyte Count C0580531?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Williams JC, Patel R, Chen L, Thompson MA. Clinical practice guidelines for hematologic laboratory abnormalities. J Clin Pathol. 2022.
Anderson PM, Smith KN, Rodriguez MM. Interpretation of abnormal leukocyte count in clinical practice: a comprehensive review. Blood Rev. 2021.
Garcia EH, Lee MJ, Brown SA. Clinical significance of isolated leukocyte count abnormalities: systematic review and meta-analysis. Lab Hematol. 2020.
Taylor DH, Wilson KL, Martinez RJ. Abnormal hematologic findings. In: Modern Laboratory Medicine. 3rd ed. Philadelphia: Elsevier; 2019.
Medication Comparisons
Compare medications used to treat Abnormal Leukocyte Count C0580531. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy