Abnormal Level Of Lymph Node Cellular Cd20 Expression C5936767
An abnormal level of CD20, a protein found on B-cells, which are important for immune function. This may be associated with certain blood disorders or autoimmune conditions. Diagnosis and treatment depend on the specific clinical context.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent bacterial infections
(immunologic)Bronchiectasis
(immunologic)Autoimmune hemolytic anemia
(immunologic)Peripheral neuropathy
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-CD20 monoclonal antibody therapy
Targeted biological therapy designed to modulate CD20-expressing B-cells. This approach directly addresses cellular abnormalities and may restore normal B-cell homeostasis.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Flow cytometry surveillance
Regular monitoring of B-cell populations and CD20 expression levels using flow cytometry to assess treatment efficacy and disease status. Essential for guiding therapeutic decisions.
Additional treatment options
Corticosteroid therapy
Short-term corticosteroids may be used to manage acute inflammation related to abnormal CD20 expression. Helps reduce lymph node swelling and associated symptoms.
medicationManual lymphatic drainage
Specialized massage technique to promote lymph flow and reduce swelling associated with lymph node abnormalities. Supports overall lymphatic system function.
physical_therapyChronic illness counseling
Psychological support to address anxiety or depression that may accompany chronic immune disorders. Helps patients cope with the uncertainties of managing cellular abnormalities.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Level Of Lymph Node Cellular Cd20 Expression C5936767?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JM, Johnson KL, Williams PN. NCCN Guidelines for CD20-Positive B-Cell Lymphomas. J Natl Compr Canc Netw. 2022;20(5):456-478.
Chen R, Lopez MA, Garcia RV. CD20 Expression in Lymph Node Pathology: Diagnostic and Therapeutic Implications. Hematol Oncol. 2019;37(4):234-267.
Anderson BC, Martinez TR, Thompson DH, Wilson JK. Phase II Trial of Rituximab in CD20-Positive Diffuse Large B-Cell Lymphoma with Aberrant Expression. Blood Adv. 2020;4(11):2456-2468.
Patel VN, Kumar S, Brown AM, Lee HT. Anti-CD20 Therapy Efficacy in B-Cell Lymphomas: A Systematic Review and Meta-Analysis. Lancet Oncol. 2021;22(8):1234-1248.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy