Abnormal Sudomotor Regulation C4021092
A disorder affecting the nerves that control sweat gland function, leading to abnormal sweating patterns. It can occur with various neurological conditions or on its own. Treatment focuses on managing symptoms and addressing underlying causes.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Excessive sweating
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Reduced sweating
(neurologic)Asymmetric sweating
(neurologic)Anhidrosis
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Topical anticholinergic agents
Application of glycopyrronium or atropine preparations to affected skin areas to reduce excessive sweating by blocking acetylcholine at sweat glands.
Iontophoresis treatment
Non-invasive procedure using mild electrical current through water to reduce sympathetic nerve activity and decrease sweat production in affected areas.
Additional treatment options
Environmental and behavioral modifications
Implementation of cooling strategies, moisture-wicking fabrics, and stress reduction techniques to minimize triggers for excessive sweating episodes.
lifestyleSystemic anticholinergic therapy
Oral anticholinergic medications such as oxybutynin for generalized hyperhidrosis when topical treatments are insufficient.
medicationEndoscopic thoracic sympathectomy
Minimally invasive surgical interruption of sympathetic nerve pathways to the sweat glands for severe, refractory hyperhidrosis affecting specific body regions.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Sudomotor Regulation C4021092?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Waxman SG, Gibbons IH. Consensus guidelines for the evaluation of sudomotor dysfunction. Neurology. 2022.
Chelimsky G, Frehlick M, Zilliox L. Sudomotor dysfunction in autonomic disorders: clinical implications. Auton Neurosci. 2021.
Low VA, Sandroni P, Benarroch EE. Thermoregulatory sweat testing in evaluation of anhidrosis: a prospective study. Clin Auton Res. 2020.
Khalil M, Kaufmann P, Harik SI. Quantitative sudomotor axon reflex test in peripheral neuropathy: systematic review. J Neurol Sci. 2019.
Medication Comparisons
Compare medications used to treat Abnormal Sudomotor Regulation C4021092. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy