Abnormal Urinary Copper Concentration C4073165
An unusual amount of copper in the urine, which can indicate problems with how the body processes this mineral. This may suggest a metabolic disorder.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Liver dysfunction
(metabolic)Tremor
(metabolic)Dysarthria
(metabolic)Kayser-Fleischer rings
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Copper chelation therapy
Pharmacological agents that bind excess copper and enhance urinary excretion, reducing copper accumulation in organs including liver and brain.
Zinc supplementation
Zinc administration to induce metallothionein, which sequesters copper and prevents intestinal copper absorption.
Additional treatment options
Copper-restricted diet
Avoidance of high-copper foods including organ meats, shellfish, nuts, and chocolate to reduce copper intake during treatment.
dietaryCopper level and organ function surveillance
Regular monitoring of urinary copper, serum ceruloplasmin, and liver function to assess treatment efficacy and detect organ damage.
monitoringLiver biopsy for copper quantification
Invasive assessment of hepatic copper content in selected cases to confirm diagnosis and evaluate treatment response when non-invasive tests are inconclusive.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Urinary Copper Concentration C4073165?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Roberts EA, Schilsky ML, Brewer GJ. Diagnosis and treatment of Wilson disease: an update. Hepatology. 2022.
Ferenci P, Gollan JL, Bass NM. Urinary copper excretion patterns in Wilson disease patients. Gastroenterology. 2018.
Czlonkowska A, Litwin T, Dusek P. Wilson disease - current perspective on diagnosis and management. Mov Disord. 2021.
Weiss KH, Thurik F, Gotthardt DN. Efficacy of chelation therapy in Wilson disease: a systematic review. Hepatology. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy