Abnormality Of Acid Base Homeostasis C0001118
This refers to disruptions in the body's acid-base balance, affecting how acidic or alkaline the blood is. It can result from various metabolic or respiratory conditions. Treatment targets the underlying cause.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Acidosis
Fatigue or weight changes
(metabolic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Alkalosis
(metabolic)Electrolyte disturbances
(metabolic)Respiratory compensation
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Acid-Base Correction Therapy
Systematic replacement of bicarbonate or acids using sodium bicarbonate, citrate, or ammonium chloride depending on whether acidosis or alkalosis is present.
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
IV Fluid and Electrolyte Management
Intravenous administration of appropriate fluids and electrolytes in acute settings to rapidly restore acid-base balance.
Additional treatment options
Arterial Blood Gas Serial Analysis
Regular blood gas and electrolyte monitoring to assess treatment response and adjust therapy accordingly.
monitoringNutritional Optimization
Targeted dietary modifications including protein intake adjustment, electrolyte supplementation, and avoiding precipitating foods or substances.
dietaryTreatment of Underlying Cause
Addressing the root etiology such as renal tubular acidosis management, diabetes control, or treatment of diarrhea causing bicarbonate loss.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Abnormality Of Acid Base Homeostasis C0001118?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kraft MD, Btaiche IF, Sacks GS. Acid-base disorders. JPEN J Parenter Enteral Nutr. 2022.
Seifter JL, Chang HY. Disorders of acid-base balance: New perspectives. Med Clin North Am. 2021.
Adeva-Andany MM, Fernandez-Fernandez N, Sanchez-Bou S. Sodium bicarbonate therapy in patients with metabolic acidosis: A systematic review and meta-analysis. J Crit Care. 2020.
Berend K. Diagnostic approach to acid-base disorders. In: Fluid, Electrolyte and Acid-Base Physiology. 5th ed. Elsevier; 2017.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy